After Gambia, Uzbekistan Health Ministry claimed on Tuesday that at least 18 children in the country have allegedly died after consuming India-manufactured cough syrup. The side effects of the syrup were reported in the city of Samarkand.

The health ministry issued a statement stating that 18 out of 21 children who consumed Noida-based Marion Biotech’s Doc-1 Max syrup while suffering from an acute respiratory disease died.

The ministry further stated that the company has marketed the drug on the company’s website as a treatment for cold and flu symptoms. The reports state that the children consumed excessive amounts of cough syrup, which contained ethylene glycol, which is considered a toxic substance.

Uzbekistan Health Ministry said the syrup was imported into the country by Quramax Medical LLC. It further stated that the deceased children took this drug at home for 2-7 days 3-4 times a day, 2.5-5 ml, which exceeds the standard dose of the drug for children.

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The drug was given to all children without a doctor’s prescription. Since paracetamol is the drug’s primary ingredient, Doc-1 Max syrup was improperly used as an anti-cold treatment on the pharmacy sellers’ advice, which caused the patients’ conditions to worsen, it added.

Preliminary laboratory tests have revealed that this series of Doctor-1 Max syrup contains ethylene glycol. The drug is toxic, and 1–2 ml/kg of a 95% concentrated solution can cause major health changes in the patient, such as vomiting, fainting, convulsions, cardiovascular problems, and acute kidney failure.

It further added, in fact, paracetamol should only be used at a body temperature of 38-38.5 C and above 1 or 2 times a day, 100-125 mg for a child under the age of one year, 200 mg for children aged 1-3 years and 250 mg – from 3 to 5 years. At normal body temperature, taking this drug is strictly prohibited.

According to the reports, a criminal case has been filed against officials of Quramax Medical and the State Center for Expertise and Standardization of Medicines under Article 186-3 of the Criminal Code (Violation of the order of retail sale of medicines containing potent substances).

Earlier this year, 66 children in Gambia allegedly died after consuming cough syrups manufactured by Haryana-based Maiden Pharmaceuticals.

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