Lifestyle

Blood Cancer drug, Ibrutinib, contributes to Hypertension – A study reveals

Researchers at the Ohio State Wexner Medical Center in a new study found that the blood cancer drug ibrutinib contributed to new or worsened hypertension within 6 months of treatment.

Published

6 years ago

October 4, 2019

[vc_row][vc_column][vc_column_text]Researchers at the Ohio State Wexner Medical Center in a new study found that the blood cancer drug, ibrutinib contributed to new or worsened hypertension within 6 months of treatment.

The research team also suggests results of the study are the first to tie ibrutinib-related hypertension to other cardiovascular issues, including atrial fibrillation.

“This study provides a clearer picture of the extent of hypertension development among patients taking ibrutinib, while allowing us to tease out what ibrutinib-related hypertension means in the long run for other cardiovascular events and survival,” said lead investigator Daniel Addison, MD, of the Ohio State Wexner Medical Center.

In an effort to know the long-term incidence, severity, and impacts of hypertension development during ibrutinib use, a study was conducted with 562 consecutive patients treated with ibrutinib for B-cell malignancies between 2009 and 2016.

The Study also evaluated the relationship of hypertension on ibrutinib to the development of other Major-Adverse-Cardiovascular-Events (MACE), including arrhythmias, myocardial infarction, stroke, heart failure, and cardiovascular death.

Further, the preventative and modulatory effects of antihypertensives, by medication-class, on ibrutinib-related hypertension were also assessed by the investigators.

Investigators observed 78.3%(440) patients developed new or worsening hypertension during the follow-up period, which had a median of 30 months.

Also Read: More than 2 eggs per day not good for your heart: Study

The study showed that new hypertension developed in 71.6% of ibrutinib-users with a time-to-50% cumulative incidence of 4.2 months while among those without preceding hypertension, 17.7% developed high-grade hypertension.

Moreover, in multivariable regression containing known predictors of MACE, new or worsened hypertension was associated with increased MACE. No single-antihypertensive class was associated with prevention or control of ibrutinib-related hypertension. However, antihypertensive initiation was associated with a lower risk of MACE , the researching team stated.

Collectively, these data suggested ibrutinib is largely associated with substantial increase in the incidence and severity of hypertension and that hypertension development may suggest a higher risk of subsequent cardiotoxic events.

In a release from American Society of Hematology, Addison noted due to the frequency of ibrutinib’s use as a treatment it is important to keep the increased risk profile in mind to protect against additional heart related issues.

“(Ibrutinib) has become ubiquitous to the treatment of many blood cancers and will continue to be applied to other cancers,” Addison said. “Accordingly, we need to find the best ways to manage high blood pressure and protect against other heart-related issues.”

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Festivals

Happy Lohri 2026 Wishes, quotes and messages to share with family and friends

Lohri 2026 will be celebrated on January 13. Here are the date, timing, significance and heartfelt wishes to share with loved ones.

Published

13 hours ago

January 13, 2026

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Lohri, one of north India’s most vibrant festivals, marks the end of the winter season and the arrival of the harvest period. Known for its colourful traditions, bonfires, folk dances and seasonal delicacies, the festival brings warmth and togetherness during the cold days of January.

In 2026, Lohri will be celebrated in mid-January, continuing the tradition of welcoming prosperity, happiness and new beginnings.

When is Lohri in 2026

According to the Druk Panchang, Lohri will be observed on Tuesday, January 13, 2026.

The auspicious time for Lohri Sankranti will begin at 03:13 pm on January 14, while Makar Sankranti will be celebrated on Wednesday, January 14, 2026.

Lohri holds cultural significance, especially in Punjab, Haryana and parts of north India, where families gather around bonfires, offer prayers, and celebrate with music, dance and traditional food such as jaggery, groundnuts and popcorn.

Happy Lohri 2026 Wishes, messages and quotes

Here are some heartfelt wishes and messages to share with family, friends and loved ones on Lohri:

Wishing you a Lohri filled with joy, happiness and prosperity. May this festival bring warmth and light to your life.
May the bonfire of Lohri burn away all your worries and bring you warmth, joy and success. Happy Lohri.
On this day of Lohri, may the divine festival fill your life with prosperity and growth. Happy Lohri to you and your loved ones.
As the fire of Lohri flourishes, may all your sorrows and troubles vanish with it. Happy Lohri to you and your family.
May the warmth of the Lohri bonfire fill your home with happiness and love. Happy Lohri.
Wishing you a harvest of joy and prosperity this Lohri. May your days be filled with happiness.
On this auspicious occasion of Lohri, may all your dreams come true.
Let the festival of Lohri bring you endless joy and abundance. Wishing you and your family a very Happy Lohri.
May the Lohri fire burn away sadness and bring warmth, joy and happiness into your life.
Sending you warm wishes for this festive season of Lohri. May it bring prosperity and success.
This Lohri, may the sweetness of jaggery and the warmth of groundnuts add happiness to your life.
May the festival of harvest fill your life with abundance and prosperity. Happy Lohri.

Featured

Happy Navratri 2025: Wishes, messages, quotes, greetings, images, and whatsApp greetings

Celebrate Navratri 2025 with heartfelt wishes, messages, quotes, and WhatsApp greetings. Share the joy of the nine nights of devotion to Maa Durga, spread positivity, and bless your loved ones with happiness, strength, and prosperity this festive season.

Published

4 months ago

September 22, 2025

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Navratri 2025, starting on September 22, is a nine-night festival dedicated to Maa Durga, celebrating the victory of good over evil. Across India and around the world, devotees mark the occasion with prayers, fasting, music, dance, and community gatherings. The festival emphasizes devotion, courage, and inner strength, and is a time to share blessings with loved ones through heartfelt Navratri wishes.

Unlike large-scale celebrations in India, many households and communities celebrate in more intimate settings, decorating homes with diyas, offering prayers at temples, and organizing dandiya nights and devotional gatherings. Traditional foods and vrat-friendly recipes are also an integral part of the celebration.

Here’s a collection of Happy Navratri wishes you can share with friends, family, and colleagues:

Wishes to Share During Navratri:

Wishing you a Navratri filled with devotion, joy, and prosperity.
May the nine nights bring peace to your home and happiness to your heart.
Let’s celebrate the spirit of Navratri with prayers, music, and love.
May Goddess Durga bless you with strength to face every challenge.
Wishing you health, harmony, and happiness this Navratri.
May these nine nights light up your life with positivity.
Sending warm Navratri wishes from my family to yours.
May every dance step and prayer you offer reach Maa Durga’s blessings.
Here’s to a Navratri that feels bright, peaceful, and full of grace.
May this festive season give you courage and clarity.

Happy Navratri Quotes:

May your prayers during these nine nights bring success and harmony.
Celebrate the spirit of Navratri with a heart full of gratitude.
Wishing you good health, prosperity, and endless joy this Navratri.
Let the divine energy of Durga guide your path this festive season.
May Goddess Durga empower you with strength, wisdom, and courage this Navratri and always.
Let us celebrate the triumph of good over evil. Happy Navratri to you and your loved ones.
May the colors of Navratri brighten your life with happiness, health, and prosperity.
On this auspicious occasion, may Maa Durga fulfill all your wishes and bless your home with peace.

Messages to Share on WhatsApp and Social Media:

Happy Navratri! May Maa Durga guide you toward wisdom and strength.
The nine nights remind us that patience and devotion bring results.
Celebrate Navratri with faith in your heart and kindness in your actions.
May you find joy in the small rituals and blessings in every prayer.
Wishing you courage to overcome negativity, just like Durga did.
Navratri is not only about fasting — it’s about feeding your soul with positivity.
May this Navratri open doors of success and peace for you.
Sending warm wishes across the miles this festive season.

Happy Navratri 2025 Greetings:

Remember: every night of Navratri is a chance to start fresh.
Happy Navratri 2025! Celebrate with love, and let blessings surround you.
May Maa Durga fill your home with peace and happiness this Navratri.
Wishing you nine nights of devotion, joy, and togetherness.
May the blessings of Navratri bring love and light into your life.
Happy Navratri! Let every day be a step toward positivity.
May this festive season strengthen bonds with family and friends.

Navratri 2025 Quotes and Inspiration:

“Navratri is not only a festival, it’s a reminder that good always wins.”
“Nine nights, nine forms, infinite blessings.”
“Strength is not given, it is awakened — just like the spirit of Durga.”
“Dance, devotion, and discipline — the rhythm of Navratri.”
“Every prayer during Navratri is a step closer to peace.”

This Navratri, let devotion, love, and positivity fill every home. Share these Navratri wishes, quotes, and messages to spread blessings and joy with friends and family.

Festivals

Happy Janmashtami 2025 wishes, messages and quotes to share

On Janmashtami 2025, share heartfelt wishes, WhatsApp messages, statuses, and quotes to spread the joy of Lord Krishna’s birth.

Published

5 months ago

August 16, 2025

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Janmashtami 2025 is being celebrated today, August 16, across India and among devotees worldwide. The festival marks the birth of Lord Krishna and is observed with fasting, devotional songs, dahi handi celebrations, and midnight prayers. On this auspicious occasion, here are some heartfelt wishes, WhatsApp messages, statuses, and greetings that you can share with your loved ones.

WhatsApp Messages for Janmashtami 2025

May Lord Krishna bless your home with peace, love, and happiness. Wishing you a divine and joyful Janmashtami!
On this auspicious day, let the melodies of Krishna’s flute bring serenity to your heart. Happy Janmashtami 2025!
May the blessings of Kanha always be with you and your family, guiding you towards the path of truth and dharma.
Celebrate this Janmashtami with love, laughter, and devotion. Jai Shri Krishna!
May the divine presence of Krishna fill your life with eternal joy and positivity. Happy Janmashtami!

Janmashtami Status Ideas

🌸 Jai Shri Krishna! Wishing everyone peace, love and divine blessings on this Janmashtami 2025. 🌸
🎶 “Where there is Krishna, there is love, where there is love, there is life.” Happy Janmashtami! 🎶
🌼 This Janmashtami, may Krishna’s flute play the music of happiness in your life. 🌼
🥛✨ Dahi handi, Krishna’s leela, and divine blessings—let’s celebrate Janmashtami with joy! ✨🥛
🙏 On Krishna Janmashtami, may the divine guide you to overcome challenges with courage and grace. 🙏

Short Janmashtami Quotes

“Krishna’s words are timeless wisdom; his life, an eternal inspiration.”
“Let love, compassion, and truth be your dharma this Janmashtami.”
“With devotion in your heart, every day can be Janmashtami.”
“Krishna teaches us to live with courage, love with purity, and guide with wisdom.”
“On this divine day, may Krishna’s blessings bring light to every corner of your life.”

Greeting Messages for Friends and Family

Wishing you and your family a blessed Janmashtami 2025! May the joy of Krishna’s birth fill your life with happiness.
Happy Krishna Janmashtami! May the teachings of Lord Krishna inspire you to walk the path of righteousness.
Celebrate this day with devotion, joy, and faith. Sending you warm wishes on this Janmashtami.
May your heart and home be filled with divine love and bliss of Lord Krishna. Happy Janmashtami!

On this sacred occasion, may Krishna bless you with wisdom, prosperity, and endless happiness.