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Amid surge in black fungus cases, pharma companies to increase production of Amphotericin B injection

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

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black fungus patient

Keeping in mind the increasing demand of anti-fungal drug Amphotericin B injection after several states has reported surge in black fungus cases across the country, the Pharma companies are scrambling to ramp up the production of antifungal drug. Though there are few cases of Black Fungus in the country, at 140 per million people, but the mortality rate is high 38 percent.

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

Sun Pharma spokesperson reportedly said there has been a sudden increase in demand for Liposomal Amphotericin B in India due to the rising cases of mucormycosis. The spokesperson said they have ramped up the production of Lambin 50 injection (Liposomal Amphotericin B) to meet the additional demand. He also said that the company is confident of increasing the production rapidly.

Amphotericin B is the primary drug required to treat cases of black fungus that damages the nose, eyes, sinuses and sometimes even the brain. In normal times there was no demand for the product. So, the companies were manufacturing only in limited quantities not exceeding tens of thousands of vials.

Another major supplier Serums and Vaccines (BSV) said that the primary focus of the company is to address the current demand for Liposomal Amphotericin B in the country due to rising fungal infection cases. The company is in touch with doctors, hospitals and stockists to meet the requirements and provide timely support. The BSV said the company is working with the government and suppliers of raw materials to expand production.

The shortages have also led to hoarding and black marketing of the drug, where the prices are quoted at 5-10 times the maximum retail price. Shortages and soaring prices in the black market have pressed the Centre and state governments into action.

Minister of State for Chemicals and Fertilisers Mansukh Mandaviya on May 18 reviewed the requirement and supply position of Amphotericin B. He said the government has chalked out a strategy with manufacturers to increase domestic production as well as to import the drug from all over the world, and assured that the shortage is expected to be resolved at the earliest.

Doctors have noted a surge in cases of black fungus amid patients who were hospitalised and recovering from Covid-19, leading to an increase in the demand for Amphotericin B. With several states like Delhi, Maharashtra, Gujarat and Karnataka reporting a shortage in the drug’s supply, people have once again turned to Twitter in an attempt to crowdsource the antifungal medicine.

Moneycontrol reported that Hospitals are reporting 10-15 times more cases over normal times. Experts have noted that prolonged use of steroids, those afflicted with diabetes and with reduced-immunity are at a higher risk of contracting the disease.

Read Also: Very heavy rain likely in some parts of Delhi, India Meteorogical Department issues orange alert

Earlier, the twitter has been flooded with SOS messages about the need of Remdesivir and Tocilizumab, have now added another drug to the list, ‘Amphotericin B’, an antifungal medicine.

India News

Congress suspends 5 Haryana MLAs over cross-voting in Rajya Sabha polls

Congress suspends five Haryana MLAs for cross-voting in Rajya Sabha elections, citing serious indiscipline and anti-party activities.

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The Congress has suspended five of its MLAs in Haryana for cross-voting during the recent Rajya Sabha elections, taking disciplinary action over what it described as “anti-party activities”.

The move came after the state unit reviewed the conduct of certain legislators during the polls, where some were found to have voted against the party’s authorised candidate.

Five MLAs suspended after disciplinary process

According to party sources, the MLAs were issued show-cause notices seeking an explanation for their actions. After reviewing their responses, the Congress disciplinary committee recommended suspension.

The decision was approved by the party leadership, including Congress president Mallikarjun Kharge, and has been implemented with immediate effect.

Party calls it ‘grave indiscipline’

Haryana Congress chief Udai Bhan said the action was necessary to uphold party discipline, stressing that defying the official party line during elections weakens organisational unity.

He said the party takes such violations seriously and will continue to act against any form of indiscipline.

Leadership backs strict action

Senior Congress leader and Leader of Opposition Bhupinder Singh Hooda supported the decision, saying it was taken after due consideration.

He noted that while Rajya Sabha elections are conducted through an open ballot system, allowing legislators some flexibility, the party retains the authority to initiate internal disciplinary action in cases of deviation.

Background

The action follows cross-voting reported during the recent Rajya Sabha elections in Haryana, which led to internal concerns within the party. The development has highlighted organisational challenges and prompted the leadership to take corrective steps to reinforce discipline.

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Harivansh set to be elected Rajya Sabha Deputy Chairperson unopposed

Harivansh is set to be elected unopposed as Rajya Sabha Deputy Chairman after no opposition nominations were filed before the deadline.

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Former Rajya Sabha Deputy Chairman Harivansh is set to be re-elected to the same post unopposed in the election due to be held later today.
The date has been fixed by the Chairman under the relevant rules governing the conduct of business in the Upper House.
According to sources, the deadline for submitting motions for the election was 12 noon on April 16. A total of five notices were received within the stipulated time, all proposing Harivansh for the post.

Multiple nominations, single candidate
The motions were submitted by members across parties, including Jagat Prakash Nadda, Nitin Nabin, Nirmala Sitharaman, Sanjay Kumar Jha, and Jayant Chaudhary, each backed by seconding members.
All five motions explicitly state that Harivansh be chosen as the Deputy Chairman of the Rajya Sabha.

No opposition nomination filed

Notably, no motion was submitted by the Opposition before the deadline. This effectively clears the path for a unanimous election, as there is no contest for the position.
As per parliamentary procedure, motions will be taken up one by one. Once any one motion is adopted by the House, the remaining motions will not be put to vote.

Likely to be elected by voice vote
In line with established practice, the first motion — expected to be moved by Nadda — may be adopted through a voice vote. Following this, the Chairman will formally declare Harivansh as elected Deputy Chairman.
After the declaration, Harivansh will be escorted to the Chair by members from both the Treasury and Opposition benches, adhering to parliamentary convention.

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Amit Shah counters delimitation concerns, says southern states to gain Lok Sabha seats

Amit Shah assures Parliament that southern states will gain Lok Sabha seats after delimitation, countering opposition criticism during the women’s reservation debate.

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Amit Shah

Union Home Minister Amit Shah on Thursday addressed concerns over the proposed delimitation exercise, asserting in the Lok Sabha that southern states will not lose representation but instead see an increase in their number of seats.

His remarks came during a heated debate linked to the implementation of women’s reservation, where opposition parties have raised fears that population-based delimitation could reduce the political weight of southern states.

Shah rejected these claims, calling them misleading, and said the proposed framework ensures fairness while expanding the overall strength of the Lok Sabha.

Seat count to rise with expansion of Lok Sabha

The government has indicated that the total number of Lok Sabha seats could increase significantly as part of the delimitation process. In this expanded House, the combined representation of southern states is expected to rise from 129 seats at present to around 195 seats.

Shah emphasised that no state will lose seats in absolute terms, and the exercise is designed to reflect population changes while maintaining balance across regions.

State-wise projections shared in Parliament

During his address, Shah also provided indicative figures for individual southern states, suggesting notable increases in representation. According to the projections:

  • Tamil Nadu could see its seats rise substantially
  • Kerala, Telangana, and Andhra Pradesh are also expected to gain additional seats
  • Karnataka’s representation may increase as well

These figures were presented to counter the argument that delimitation would disproportionately favour northern states.

Political debate intensifies over linkage with women’s quota

The delimitation exercise has been closely linked to the rollout of women’s reservation, which proposes one-third seats for women in Parliament and state assemblies.

Opposition leaders have questioned this linkage, arguing that tying reservation to delimitation could delay its implementation and raise federal concerns. Some leaders have also warned that the move could impact national unity if apprehensions among states are not addressed.

The government, however, maintains that the reforms are necessary to ensure equitable representation and to align the electoral system with demographic realities.

Centre dismisses ‘false narrative’ on southern states

Shah reiterated that concerns about southern states losing influence are unfounded. He said the delimitation process will increase representation across regions and described the criticism as a “false narrative” aimed at creating confusion.

The issue is expected to remain a key flashpoint as Parliament continues discussions on the women’s reservation framework and related legislative changes.

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