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Amid surge in black fungus cases, pharma companies to increase production of Amphotericin B injection

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

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black fungus patient

Keeping in mind the increasing demand of anti-fungal drug Amphotericin B injection after several states has reported surge in black fungus cases across the country, the Pharma companies are scrambling to ramp up the production of antifungal drug. Though there are few cases of Black Fungus in the country, at 140 per million people, but the mortality rate is high 38 percent.

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

Sun Pharma spokesperson reportedly said there has been a sudden increase in demand for Liposomal Amphotericin B in India due to the rising cases of mucormycosis. The spokesperson said they have ramped up the production of Lambin 50 injection (Liposomal Amphotericin B) to meet the additional demand. He also said that the company is confident of increasing the production rapidly.

Amphotericin B is the primary drug required to treat cases of black fungus that damages the nose, eyes, sinuses and sometimes even the brain. In normal times there was no demand for the product. So, the companies were manufacturing only in limited quantities not exceeding tens of thousands of vials.

Another major supplier Serums and Vaccines (BSV) said that the primary focus of the company is to address the current demand for Liposomal Amphotericin B in the country due to rising fungal infection cases. The company is in touch with doctors, hospitals and stockists to meet the requirements and provide timely support. The BSV said the company is working with the government and suppliers of raw materials to expand production.

The shortages have also led to hoarding and black marketing of the drug, where the prices are quoted at 5-10 times the maximum retail price. Shortages and soaring prices in the black market have pressed the Centre and state governments into action.

Minister of State for Chemicals and Fertilisers Mansukh Mandaviya on May 18 reviewed the requirement and supply position of Amphotericin B. He said the government has chalked out a strategy with manufacturers to increase domestic production as well as to import the drug from all over the world, and assured that the shortage is expected to be resolved at the earliest.

Doctors have noted a surge in cases of black fungus amid patients who were hospitalised and recovering from Covid-19, leading to an increase in the demand for Amphotericin B. With several states like Delhi, Maharashtra, Gujarat and Karnataka reporting a shortage in the drug’s supply, people have once again turned to Twitter in an attempt to crowdsource the antifungal medicine.

Moneycontrol reported that Hospitals are reporting 10-15 times more cases over normal times. Experts have noted that prolonged use of steroids, those afflicted with diabetes and with reduced-immunity are at a higher risk of contracting the disease.

Read Also: Very heavy rain likely in some parts of Delhi, India Meteorogical Department issues orange alert

Earlier, the twitter has been flooded with SOS messages about the need of Remdesivir and Tocilizumab, have now added another drug to the list, ‘Amphotericin B’, an antifungal medicine.

India News

PM Modi accuses Congress of anti-Sikh bias over Rahul Gandhi’s ‘traitor’ remark

Prime Minister Narendra Modi accused Rahul Gandhi of targeting BJP MP Ravneet Singh Bittu with a ‘gaddar’ remark because of his Sikh identity while speaking in the Rajya Sabha.

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PM Modi

Prime Minister Narendra Modi on Wednesday launched a sharp attack on Leader of the Opposition Rahul Gandhi, alleging that his “traitor” remark against BJP MP Ravneet Singh Bittu reflected the Congress party’s animosity towards the Sikh community.

The Prime Minister made the remarks in the Rajya Sabha while replying to the motion of thanks on the President’s address. Referring to an incident in the Parliament complex a day earlier, Modi said Gandhi’s comment had crossed all limits of political decency.

The controversy stems from a protest by suspended Opposition MPs, during which Ravneet Singh Bittu — a former Congress leader who joined the BJP ahead of the 2024 Lok Sabha elections — allegedly made a remark suggesting the protesters were behaving as if they had won a war.

In response, Rahul Gandhi was heard saying, “A traitor is walking by, look at his face,” before approaching Bittu and extending his hand. Gandhi then reportedly added, “Hello, brother. My traitor friend. Don’t worry, you will come back.”

Bittu refused to shake hands with the Congress leader and instead described him as an “enemy of the country” before walking away from the scene.

While the Congress later clarified that Gandhi’s remark was aimed at Bittu for leaving the party, the BJP seized upon the comment, calling it an insult to the Sikh community. Protests were subsequently held by members of the Sikh community outside the Congress headquarters and at other locations.

Addressing the House, Prime Minister Modi said that many leaders had quit the Congress in the past and that the party itself had split multiple times, but none of those leaders had been labelled a traitor. “He called this MP a traitor because he is Sikh,” the Prime Minister alleged, as treasury bench members raised slogans condemning the remark.

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Manipur Assembly to meet at 4 pm today, floor test likely under new chief minister

The Manipur Legislative Assembly will convene at 4 pm today, with a floor test likely as the new chief minister seeks to prove his majority in the House.

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Manipur assembly

The Manipur Legislative Assembly will convene at 4 pm on Thursday in Imphal, a day after Yumnam Khemchand Singh was sworn in as the chief minister. A floor test is likely to be held on the first day of the session to establish the majority of the newly formed government.

In the 60-member Assembly, the BJP holds 37 seats, while its ally National People’s Party has six members, giving the ruling combine a clear majority in the House.

Singh chaired the first Cabinet meeting of his government late Wednesday evening, shortly after taking oath as the 13th chief minister of Manipur. The meeting marked the formal start of administrative functioning under the new Council of Ministers.

His appointment came nearly a year after the resignation of former chief minister N Biren Singh, who stepped down following months of ethnic violence between the Meitei and Kuki communities in the state.

After taking oath, Singh thanked Prime Minister Narendra Modi and said he would work with “utmost diligence to advance development and prosperity in Manipur,” aligning the state’s efforts with the vision of Viksit Bharat.

He said the government’s focus would be on inclusive economic growth while preserving Manipur’s cultural heritage, adding that he would discharge his responsibilities with sincerity and dedication, mindful of the trust placed in him.

The summoning of the 12th Manipur Legislative Assembly by Governor Ajay Kumar Bhalla, along with the first Cabinet meeting, signals the resumption of legislative and administrative processes in the state, officially bringing President’s rule to an end.

The sixth session of the 12th Manipur Legislative Assembly was last held from July 31 to August 12, 2024.

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India News

PM Modi skips Lok Sabha reply as protests force repeated adjournments

PM Modi did not deliver his Lok Sabha reply today after sustained Opposition protests led to repeated adjournments over a dispute involving Rahul Gandhi’s proposed speech.

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PM Modi

Prime Minister Narendra Modi did not deliver his scheduled reply to the Motion of Thanks on the President’s address in the Lok Sabha today after sustained Opposition protests led to multiple adjournments of the House.

The disruption followed an escalation of tensions linked to Congress leader Rahul Gandhi’s proposed speech and the suspension of eight Opposition MPs a day earlier. The situation worsened after remarks made by BJP MP Nishikant Dubey during the proceedings.

Dispute over references to books sparks fresh ruckus

The controversy intensified when Nishikant Dubey responded to Rahul Gandhi’s demand to speak on national security and references to the unpublished memoirs of former Army chief General MM Naravane. Dubey said that while Gandhi wanted to quote from an unpublished book, he himself had brought several books that, according to him, made claims about the Gandhi family.

As Dubey began listing these books and their contents, strong protests erupted from Opposition members. Krishna Prasad Tenneti, who was presiding over the House at the time, cited Rule 349, which restricts members from reading out books, newspapers, or letters unless directly related to parliamentary business. Despite repeated warnings, the matter remained unresolved, leading to another adjournment.

Rahul Gandhi accuses government of silencing debate

Earlier in the day, Rahul Gandhi alleged that he was being prevented from speaking on an issue of national importance. He claimed the government was uncomfortable with references to General Naravane’s memoirs, which he said discussed the handling of the 2020 China border crisis.

In a social media post, Gandhi said he intended to present the Prime Minister with a book authored by the former Army chief, adding that some cabinet ministers had even questioned the existence of the book. He also wrote to Lok Sabha Speaker Om Birla after the suspension of eight Opposition MPs, alleging that parliamentary debate was being curtailed.

After it became clear that the Prime Minister would not speak in the House today, Gandhi posted that PM Modi had avoided Parliament because he was “scared” to face the truth. Congress MP Priyanka Gandhi Vadra echoed the allegation, claiming the Prime Minister was unwilling to enter the House.

Proceedings disrupted throughout the day

Lok Sabha proceedings were first adjourned until 2 pm amid loud protests over the issue linked to Naravane’s memoirs. Even after the House reconvened, disruptions continued, preventing normal business from resuming.

Later, Congress MPs staged a demonstration outside the Parliament complex, demanding that Rahul Gandhi be allowed to speak on the President’s address.

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