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Amid surge in black fungus cases, pharma companies to increase production of Amphotericin B injection

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

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black fungus patient

Keeping in mind the increasing demand of anti-fungal drug Amphotericin B injection after several states has reported surge in black fungus cases across the country, the Pharma companies are scrambling to ramp up the production of antifungal drug. Though there are few cases of Black Fungus in the country, at 140 per million people, but the mortality rate is high 38 percent.

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

Sun Pharma spokesperson reportedly said there has been a sudden increase in demand for Liposomal Amphotericin B in India due to the rising cases of mucormycosis. The spokesperson said they have ramped up the production of Lambin 50 injection (Liposomal Amphotericin B) to meet the additional demand. He also said that the company is confident of increasing the production rapidly.

Amphotericin B is the primary drug required to treat cases of black fungus that damages the nose, eyes, sinuses and sometimes even the brain. In normal times there was no demand for the product. So, the companies were manufacturing only in limited quantities not exceeding tens of thousands of vials.

Another major supplier Serums and Vaccines (BSV) said that the primary focus of the company is to address the current demand for Liposomal Amphotericin B in the country due to rising fungal infection cases. The company is in touch with doctors, hospitals and stockists to meet the requirements and provide timely support. The BSV said the company is working with the government and suppliers of raw materials to expand production.

The shortages have also led to hoarding and black marketing of the drug, where the prices are quoted at 5-10 times the maximum retail price. Shortages and soaring prices in the black market have pressed the Centre and state governments into action.

Minister of State for Chemicals and Fertilisers Mansukh Mandaviya on May 18 reviewed the requirement and supply position of Amphotericin B. He said the government has chalked out a strategy with manufacturers to increase domestic production as well as to import the drug from all over the world, and assured that the shortage is expected to be resolved at the earliest.

Doctors have noted a surge in cases of black fungus amid patients who were hospitalised and recovering from Covid-19, leading to an increase in the demand for Amphotericin B. With several states like Delhi, Maharashtra, Gujarat and Karnataka reporting a shortage in the drug’s supply, people have once again turned to Twitter in an attempt to crowdsource the antifungal medicine.

Moneycontrol reported that Hospitals are reporting 10-15 times more cases over normal times. Experts have noted that prolonged use of steroids, those afflicted with diabetes and with reduced-immunity are at a higher risk of contracting the disease.

Read Also: Very heavy rain likely in some parts of Delhi, India Meteorogical Department issues orange alert

Earlier, the twitter has been flooded with SOS messages about the need of Remdesivir and Tocilizumab, have now added another drug to the list, ‘Amphotericin B’, an antifungal medicine.

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Enforcement Directorate says Arvind Kejriwal is deliberately eating mangoes, sweets, taking sugar with tea to increase his blood sugar level and create ground for bail

The Enforcement Directorate (ED) made the claim before special judge for ED and CBI cases, Kaveri Baweja, who gave directions to the Tihar jail authorities to file a report in the matter which should also include Kejriwal’s diet chart.

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The Enforcement Directorate told the court on Thursday that Delhi Chief Minister Arvind Kejriwal, arrested in liquor policy case, is taking high sugar intake like mangoes and sweets every day deliberately in spite of suffering from type 2 diabetes so that he can create grounds for medical bail. The Enforcement Directorate (ED) made the claim before special judge for ED and CBI cases, Kaveri Baweja, who gave directions to the Tihar jail authorities to file a report in the matter which should also include Kejriwal’s diet chart.

Kejriwal had moved court and also sought permission to consult his regular doctor via video conference because his sugar levels were fluctuating. The judge directed the authorities concerned to file the report by tomorrow, when the court will take up the matter again.

 Advocate Vivek Jain, counsel for Delhi CM Arvind Kejriwal responded to the ED’s argument and said this is an issue made by Enforcement Directorate so that home-cooked food should also be stopped. He said this would have a major impact on his health. Advocate Jain added that whatever Kejriwal is eating is as per his doctors prescribed dietary chart. He said the matter is sub judice and they do not have anything to say.

Advocate Vivek Jain objected to the Enforcement Directorate’s submission and said that the agency is making these allegations only for the media. He said that some toffee and other things are given to diabetic patients so that they can maintain their sugar levels. Jain added that Kejriwal is withdrawing his application and will file a better one later.

AAP minister Atishi Marlena said that Arvind Kejriwal had fallen ill and lost about 4.5 kg since his arrest on March 21. She addressed a press conference where the AAP leader said, Arvind Kejriwal is a severe diabetes patient but he never lets his health issue come as the way of his in the service to the nation.

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Enforcement Directorate seizes Shilpa Shetty’s husband Raj Kundra’s properties worth Rs 97 crore

The Enforcement Directorate said in a statement that the Mumbai zonal office of ED has provisionally attached immovable and movable properties of Kundra under the provisions of Prevention of Money Laundering Act (PMLA), 2002.

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The Enforcement Directorate on Thursday seized businessman Raj Kundra’s properties worth Rs 97.79 crore. The siezed properties include a residential flat in Mumbai’s Juhu, which is named after his wife and Bollywood actor Shilpa Shetty.  The Enforcement Directorate said the seized properties include another property which is a residential bungalow in Pune and Equity shares in the name of Raj Kundra.

The Enforcement Directorate said in a statement that the Mumbai zonal office of ED has provisionally attached immovable and movable properties of Kundra under the provisions of Prevention of Money Laundering Act (PMLA), 2002. The Enforcement Directorate began the investigation on the basis of a number of FIRs which were registered by Delhi Police and Maharashtra Police. It is being said that Kundra collected large sums of money in the form of bitcoins which were worth Rs 6,600 crore in 2017 from the public with the false promises of 10 % monthly return in the form of bitcoins.

The ED said that it was planned that the collected bitcoins will be used for bitcoin mining and investors will get to get a large return in Crypto assets. But the promoters cheated the investors as they concealed the ill-gotten bitcoins in obscure online wallets. The Enforcement Directorate revealed in its investigation that Raj Kundra received 285 bitcoins from the mastermind and promoter of Gain Bitcoin Ponzi Scam Amit Bhardwaj for setting up bitcoin mining farm in Ukraine.

The Enforcement Directorate in its statement said that the bitcoins were sourced out of proceeds of crime collected by Amit Bhardwaj from gullible investors. Since the deal did not go through, so Kundra is still in possession and enjoyment of 285 bitcoins which are valued at more than Rs 150 crore. Earlier a number of search operations were conducted in connection with this case, leading to the arrest of three people — Simpy Bhardwaj on December 17, 2023, Nitin Gaur on December 29, 2023, and Nikhil Mahajan on January 16, 2023.

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Religious outfit vandalises The Blessed Mother Teresa High School in Telangana after teachers object to students wearing Hanuman Deeksha dress

The Religious group broke glass windows and flower pots and pelted stones on the statue of St. Mother Teresa at the school’s entrance. The religious outfit also attacked Father Jaimon Joseph, the school manager.

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A religious group shouting Jai Shri Ram has vandalised a Catholic school and assaulted a priest in Telangana’s Mancherial district on Tuesday. The saffron mob staged protest and vandalised The Blessed Mother Teresa High School in Kannepally village. They broke glass windows and flower pots and pelted stones on the statue of St. Mother Teresa at the school’s entrance. The religious outfit also attacked Father Jaimon Joseph, the school manager.

The priest who is a member of the Missionary Congregation of the Blessed Sacrament (MCBS) said some of members of the mob even slapped and threw punches at him while others attacked him from behind. The religious outfit accused the school management of not allowing Hindu students to wear their religious costumes. The school authorities said the allegation made by the mob is misleading and has no truth in it.

Earlier, the students who wore religious costumes had informed the school principal that it was part of a 21-day special religious practice. The principal said he had only asked the students to bring their parents to school after noticing that they are not wearing the school uniform.

Later, members of the religious outfit started protesting outside the school. They demanded action should be taken against the management for stopping the students from entering the school and appearing for their annual examinations as they were wearing the Hanuman deeksha dress.

The priest said soon after the video started circulating on social media and became viral with hate messages against Christians. After this incident many Hindus reached the school and vandalized it. A complaint has been lodged at the local police station by the school management, but no arrests have been made so far. Instead of taking action against the miscreants, the police have filed a case against the school management for hurting religious sentiments of the local people.

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