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Amid surge in black fungus cases, pharma companies to increase production of Amphotericin B injection

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

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Keeping in mind the increasing demand of anti-fungal drug Amphotericin B injection after several states has reported surge in black fungus cases across the country, the Pharma companies are scrambling to ramp up the production of antifungal drug. Though there are few cases of Black Fungus in the country, at 140 per million people, but the mortality rate is high 38 percent.

The industry source hinted that it would take at least 15-30 days for new production to enter the market, as the drug is complex to manufacture and would require a certain number of days of sterility data before the batch is released.

Sun Pharma spokesperson reportedly said there has been a sudden increase in demand for Liposomal Amphotericin B in India due to the rising cases of mucormycosis. The spokesperson said they have ramped up the production of Lambin 50 injection (Liposomal Amphotericin B) to meet the additional demand. He also said that the company is confident of increasing the production rapidly.

Amphotericin B is the primary drug required to treat cases of black fungus that damages the nose, eyes, sinuses and sometimes even the brain. In normal times there was no demand for the product. So, the companies were manufacturing only in limited quantities not exceeding tens of thousands of vials.

Another major supplier Serums and Vaccines (BSV) said that the primary focus of the company is to address the current demand for Liposomal Amphotericin B in the country due to rising fungal infection cases. The company is in touch with doctors, hospitals and stockists to meet the requirements and provide timely support. The BSV said the company is working with the government and suppliers of raw materials to expand production.

The shortages have also led to hoarding and black marketing of the drug, where the prices are quoted at 5-10 times the maximum retail price. Shortages and soaring prices in the black market have pressed the Centre and state governments into action.

Minister of State for Chemicals and Fertilisers Mansukh Mandaviya on May 18 reviewed the requirement and supply position of Amphotericin B. He said the government has chalked out a strategy with manufacturers to increase domestic production as well as to import the drug from all over the world, and assured that the shortage is expected to be resolved at the earliest.

Doctors have noted a surge in cases of black fungus amid patients who were hospitalised and recovering from Covid-19, leading to an increase in the demand for Amphotericin B. With several states like Delhi, Maharashtra, Gujarat and Karnataka reporting a shortage in the drug’s supply, people have once again turned to Twitter in an attempt to crowdsource the antifungal medicine.

Moneycontrol reported that Hospitals are reporting 10-15 times more cases over normal times. Experts have noted that prolonged use of steroids, those afflicted with diabetes and with reduced-immunity are at a higher risk of contracting the disease.

Read Also: Very heavy rain likely in some parts of Delhi, India Meteorogical Department issues orange alert

Earlier, the twitter has been flooded with SOS messages about the need of Remdesivir and Tocilizumab, have now added another drug to the list, ‘Amphotericin B’, an antifungal medicine.

India News

Nitish Kumar’s son Nishant among 32 inducted in Bihar cabinet expansion

Nishant Kumar entered the Bihar cabinet for the first time as 32 ministers from NDA allies took oath in a major expansion of the state government.

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Bihar government cabinet

A major cabinet expansion took place in Bihar on Thursday, with 32 leaders from the ruling NDA alliance inducted into the state government. Among the prominent names was Nishant Kumar, son of former Bihar chief minister Nitish Kumar, who entered the cabinet for the first time.

The expansion included representatives from all major NDA allies in the state. According to reports, the BJP secured 15 ministerial berths, while JD(U) got 13 positions. Two ministers were inducted from Lok Janshakti Party (Ram Vilas), while Hindustani Awam Morcha and Rashtriya Lok Morcha received one berth each.

The oath-taking ceremony was held in Patna in the presence of senior NDA leaders, including Prime Minister Narendra Modi, Union Home Minister Amit Shah and Defence Minister Rajnath Singh.

Nishant Kumar’s induction comes weeks after he formally entered active politics. His entry into the Bihar cabinet is being viewed as a significant development for JD(U), which had long projected an anti-dynasty image under Nitish Kumar’s leadership.

The cabinet reshuffle follows Nitish Kumar’s move to the Rajya Sabha earlier this year and the formation of the government led by Chief Minister Samrat Choudhary.

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PM Modi marks Operation Sindoor anniversary, calls it India’s firm stand against terrorism

PM Modi said Operation Sindoor showcased India’s firm response against terrorism while paying tribute to the armed forces on the operation’s first anniversary.

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PM Modi

Prime Minister Narendra Modi on Thursday said Operation Sindoor demonstrated India’s firm response against terrorism and highlighted the country’s commitment to national security.

Marking one year of the operation, the Prime Minister praised the courage, precision and professionalism of the Indian armed forces. He said the military action was carried out in response to the Pahalgam terror attack that had claimed the lives of 26 civilians in 2025.

Operation Sindoor was launched on May 7, 2025, as a calibrated tri-services operation targeting terror infrastructure linked to cross-border terrorism. Reports said the operation showcased coordinated action by the armed forces and was seen as a major counter-terror response by India.

On the anniversary of the operation, PM Modi also changed the display pictures across his social media platforms, including X, Facebook, Instagram and WhatsApp. The image carried the text “Operation Sindoor” along with the Indian tricolour design.

The Indian Air Force also shared visuals and messages recalling the operation and highlighting India’s military response. A video released by the force described the operation as a strong message against terrorism and referred to the precision strikes carried out during the mission.

Operation Sindoor was launched following the Pahalgam terror attack, after which India carried out strikes on terror camps in Pakistan and Pakistan-occupied Kashmir, according to official statements and reports published at the time.

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Vijay meets Tamil Nadu Governor again as TVK pushes to prove majority

TVK chief Vijay held another meeting with Tamil Nadu Governor Rajendra Vishwanath Arlekar as the party intensified efforts to secure majority support after emerging as the single-largest party in the Assembly elections.

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Actor vijay

Actor-turned-politician Vijay met Tamil Nadu Governor Rajendra Vishwanath Arlekar again on Thursday as his party, Tamilaga Vettri Kazhagam (TVK), continued efforts to prove it has enough support to form the next government in the state.

TVK emerged as the single-largest party in the 234-member Tamil Nadu Assembly after winning 108 seats, but it remains short of the majority mark of 118.

The Congress has extended support to TVK, adding five MLAs to Vijay’s side. However, the alliance still needs additional backing from other parties or independents to comfortably cross the halfway mark.

According to reports, the Governor has not yet been fully convinced that TVK currently has the required numbers to form a stable government. This has delayed clarity over the swearing-in ceremony and the formal invitation to form the government.

Political activity intensified after reports emerged that some AIADMK legislators were moved to a resort in Puducherry amid speculation over possible support to TVK. AIADMK leaders, however, publicly denied any internal crisis.

TVK sources have expressed confidence that the party will be able to demonstrate majority support during discussions with the Governor.

The Tamil Nadu election results marked a major political shift in the state, with TVK breaking the long-standing dominance of the DMK and AIADMK in its first Assembly election contest.

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