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Mixing of Covid vaccine doses could be more effective against mutations, AIIMS chief says need more data before taking decision

The AIIMS chief Dr Randeep Guleria suggested that the mixing of two different Covid vaccine doses may improve their efficacy against Covid-19 but need more data before taking any decision. Speaking with NDTV he said early studies indicate that combining two different shots could be an alternative.

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AIIMS Chief Dr Randeep Guleria

Amid fears that mixing doses of two different vaccines could be ineffective against various and more powerful Covid variants, AIIMS chief Dr Randeep Guleria on Saturday suggested that the though mixing vaccines may improve their efficacy against Covid-19, there was need for more data before taking a decision.

Speaking to NDTV, Guleria said for battling against more infectious variants like Delta Plus and Delta is possible by mixing two different Covid-19 vaccines doses. He said early studies indicate that combining two different shots could be an alternative.

Last month, the Centre announced that as part of its new immunisation policy, government experts will investigate different combinations of Covid-19 vaccine doses to see whether they improve efficacy.

Guleria said the government is working on mixing of two different Covid vaccine doses and results of trials will be available in a few months. However, the doctors are searching which two vaccines could be combined for effective results. He stressed the importance of being vaccinated despite these fears.

Last month, preliminary results of a British study published in The Lancet where participants were given a first dose of Covishield and a second of Pfizer had reported more short-lived side-effects while the data on efficacy is still pending. Another Spanish study found the combination to be safe and effective.

On the Delta Plus variant, Dr Guleria said the government is closely monitoring the situation but the Delta strain is of more immediate concern for the Central government. There are 48 cases of Delta Plus variants in 11 states, the government said Friday.

Delta Plus is a mutation of the Delta variation discovered in India and is thought to be responsible for the disastrous second wave that hit the country in April-May.

Several specialists have speculated that the Delta Plus version could trigger a third wave in the near future, while the top doctor has stated that a potential third wave is not likely to be as catastrophic as the second.

The Covid second wave hit India hard with lakhs infected and thousands dying every day as the wave have ended up 4,000 deaths per day. Worryingly, the number of deaths in some states has since been revised amid accusations of undercounting; the new data suggests lakhs of deaths were ignored or not reported. The second wave also triggered a massive healthcare crisis – hospitals struggled to deal with the influx of patients and critical resources like oxygen, medicines and ventilators were scarce.

Dr Guleria, like other experts, has warned against rushing to lift Covid restrictions, particularly if there is even a slight surge in cases.

2024 Lok Sabha Elections

Bollywood actor Neha Sharma campaigns for her father Ajit Sharma in Bhagalpur, Bihar

The Bollywood actor posted a video on her Instagram handle which showed her journey through various districts of Bihar, including Kishanganj, Banka, Purnea and Katihar. She was dressed in a traditional salwar kameez and was seen greeting and encouraging the public to cast their votes.

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Bollywood actor Neha Sharma’s recent participation in a roadshow in Bihar has taken the internet by storm. Sharma, known for her roles in films like Tum Bin 2 and Crook, was seen supporting her father, Ajit Sharma, who is contesting from Bhagalpur Lok Sabha seat on a Congress ticket. The roadshow came amid speculations that the actor might enter politics. But, it is now clear that she was just campaigning for her father.

neha sharma

The Bollywood actor posted a video on her Instagram handle which showed her journey through various districts of Bihar, including Kishanganj, Banka, Purnea and Katihar. She was dressed in a traditional salwar kameez and was seen greeting and encouraging the public to cast their votes.

The actor received a warm reception and love from a large crowd in Pirpainti and Kahalgaon during her roadshow. She wrote on Instagram that it is said when someone gives one a place in their heart, then they live there forever. She said her heart is full of all the love and support she was receiving from the people. She thanked the people for the warm welcome she got in Pirpainti and Kahalgaon. Aapka pyar sar ankhon par.

Another video, circulating on social media showed the actor actively participating in her father’s election campaign in Bhagalpur. The election to the Bhagalpur Lok Sabha seat is set to take place in the 2nd phase on April 26. Ajit Sharma is representing the Congress and is up against JDU’s Ajay Kumar Mandal in this seat.

Earlier, there had been rumours and speculations that Neha Sharma might join politics. But many reports have clarified that she is not making her political debut yet. The Bollywood actor had been offered the opportunity to join politics by her father Ajjit Sharma but she is currently focusing on her acting career.

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Education

Farmer’s son Nilkrishna Gajare Nirmalkumar from Maharashtra scores 100 NTA score in IIT-JEE Mains 2024

Nilkrishna Gajare’s father is a farmer and had to discontinue his own education after Class 12 as he faced financial difficulties. Gajare faced financial challenges growing up. However, his unwavering dedication and strategic approach to preparation set him apart from the crowd.

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Nilkrishna Gajare, who hails from Maharashtra’s Washim, achieved an extraordinary feat by securing a perfect score of 100 in the JEE Main 2024 examination. His journey from humble beginnings to the pinnacle of success is a source of inspiration for many people.

Nilkrishna Gajare’s father is a farmer and had to discontinue his own education after Class 12 as he faced financial difficulties. Gajare faced financial challenges growing up. However, his unwavering dedication and strategic approach to preparation set him apart from the crowd, which resulted in his remarkable achievement of emerging as topper of one of India’s toughest Engineering entrance exams.

Nilkrishna Gajare had a strategic plan that helped him succeed in IIT-JEE 2024. According to Nilkrishna persistence is important and one should never stop trying until they understand a topic. He said being curious and asking questions are important traits of a good student.  He said one should not be ashamed of asking questions.

Nilkrishna spent around 10-15 hours every day studying on his own for the JEE Main exam. He mentioned that he used his class notes for Physics and Physical Chemistry. For organic chemistry and inorganic chemistry, he relied on both notes and practice questions.

As for Mathematics, he believed that practicing regularly was the most important thing for him. Other interests of Nilkrishna include archery. He has participated at both state and national levels, and he finds joy in the sport.  He said archery helps him understand the importance of focusing his attention on his goals. Nilkrishna likes watching movies and said they are a great source of enjoyment and relaxation.

He likes to watch a movie after exams and occasionally treats himself to one each week too. Gajare aims to keep up the pace for the JEE-Advanced exam and hopes to get into the IITs. He said he wants to secure admission in IIT-Bombay in the computer science branch.

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2024 Lok Sabha Elections

Lok Sabha elections: Samajwadi Party chief Akhilesh Yadav files nomination from Kannauj

The Samajwadi Party has announced Akhilesh Yadav as its official candidate for the Kannauj Lok Sabha seat today

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Samajwadi Party (SP) chief Akhilesh Yadav, submitted his nomination for the Kannauj Lok Sabha constituency ahead of tomorrow’s second round of voting. In front of Ram Gopal Yadav and other party leaders, the chief of the SP, who had previously contested the seat in 2000, 2004 and 2009, submitted the nomination.

Speaking with media, Ram Gopal Yadav said that SP would win the seat by a huge margin. The BJP candidate might lose his deposit in the seat, he said.

The Samajwadi Party has completely reversed its earlier plan to field former Mainpuri MP Tej Pratap Singh Yadav as their candidate, which is a significant political development.

Earlier, Akhilesh Yadav told reporters, people will find out when the nomination takes place, in reference to the speculations that he will contest for the seat. The historic victory of Kannauj is the subject of inquiry.

The former chief minister continued, the people have decided that the India bloc is coming as the future and the BJP will be history in this election.

Notably, elections for the Kannauj seat are scheduled for May 13, which would intensify the political drama that is now playing out in Uttar Pradesh. Previously regarded as the Samajwadi Party’s stronghold, the seat was lost by the party in the 2019 election when Subrat Pathak of the BJP won with a resounding victory.

The candidates competing for the following Uttar Pradesh seats will find out their destiny in the second round of voting, which is scheduled for tomorrow, Amroha, Meerut, Mathura, Baghpat, Aligarh, Ghaziabad, Gautam Buddh Nagar, and Bulandshahar.

Notably, two Bollywood celebrities running as BJP candidates in the second round are Hema Malini from Mathura and Arun Govil from Meerut. There are 91 contestants from UP competing in the second phase.

The seats in Gautam Buddha Nagar and Mathura are up for grabs, with a maximum of 15 applicants per seat. In Bulandshahr, six candidates are vying for the presidency. There are twelve contenders running in Amroha, eight in Meerut, seven in Baghpat, and fourteen in Ghaziabad and Aligarh.

1,67,77,198 votes will decide these candidates’ fates.

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