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Mixing of Covid vaccine doses could be more effective against mutations, AIIMS chief says need more data before taking decision

The AIIMS chief Dr Randeep Guleria suggested that the mixing of two different Covid vaccine doses may improve their efficacy against Covid-19 but need more data before taking any decision. Speaking with NDTV he said early studies indicate that combining two different shots could be an alternative.

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AIIMS Chief Dr Randeep Guleria

Amid fears that mixing doses of two different vaccines could be ineffective against various and more powerful Covid variants, AIIMS chief Dr Randeep Guleria on Saturday suggested that the though mixing vaccines may improve their efficacy against Covid-19, there was need for more data before taking a decision.

Speaking to NDTV, Guleria said for battling against more infectious variants like Delta Plus and Delta is possible by mixing two different Covid-19 vaccines doses. He said early studies indicate that combining two different shots could be an alternative.

Last month, the Centre announced that as part of its new immunisation policy, government experts will investigate different combinations of Covid-19 vaccine doses to see whether they improve efficacy.

Guleria said the government is working on mixing of two different Covid vaccine doses and results of trials will be available in a few months. However, the doctors are searching which two vaccines could be combined for effective results. He stressed the importance of being vaccinated despite these fears.

Last month, preliminary results of a British study published in The Lancet where participants were given a first dose of Covishield and a second of Pfizer had reported more short-lived side-effects while the data on efficacy is still pending. Another Spanish study found the combination to be safe and effective.

On the Delta Plus variant, Dr Guleria said the government is closely monitoring the situation but the Delta strain is of more immediate concern for the Central government. There are 48 cases of Delta Plus variants in 11 states, the government said Friday.

Delta Plus is a mutation of the Delta variation discovered in India and is thought to be responsible for the disastrous second wave that hit the country in April-May.

Several specialists have speculated that the Delta Plus version could trigger a third wave in the near future, while the top doctor has stated that a potential third wave is not likely to be as catastrophic as the second.

The Covid second wave hit India hard with lakhs infected and thousands dying every day as the wave have ended up 4,000 deaths per day. Worryingly, the number of deaths in some states has since been revised amid accusations of undercounting; the new data suggests lakhs of deaths were ignored or not reported. The second wave also triggered a massive healthcare crisis – hospitals struggled to deal with the influx of patients and critical resources like oxygen, medicines and ventilators were scarce.

Dr Guleria, like other experts, has warned against rushing to lift Covid restrictions, particularly if there is even a slight surge in cases.

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Congress, BJP attack Bhagwant Mann over remarks on Punjab blasts

Congress and BJP have jointly criticised Punjab CM Bhagwant Mann after he linked recent blasts near defence sites to political motives, triggering a controversy.

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Bhagwant Mann

A political row has erupted in Punjab after Chief Minister Bhagwant Mann linked recent blast incidents to political motives, drawing sharp criticism from both the Congress and the Bharatiya Janata Party (BJP).

The controversy follows two low-intensity explosions reported within a short span of time — one near the Border Security Force (BSF) headquarters in Jalandhar and another close to an army cantonment area in Amritsar. The incidents raised concerns over security, particularly given the sensitive nature of the locations.

In response, Mann suggested that the blasts could be part of a larger political strategy. His remarks triggered a strong backlash, with opposition parties accusing him of politicising a serious security issue.

Leaders from the Congress criticised the Chief Minister’s statement, calling it inappropriate and alleging that such comments undermine the gravity of the situation. They stressed that matters related to national security should be handled with caution and responsibility.

The BJP also joined the criticism, questioning the basis of Mann’s claims and urging the state government to focus on investigation and law enforcement instead of making political allegations.

The developments have led to an unusual moment where both Congress and BJP appear aligned in their criticism of the Aam Aadmi Party-led government in the state.

Meanwhile, the blasts themselves have intensified concerns over safety in border regions, with authorities continuing their investigation into the incidents. No casualties were reported, but the proximity to defence establishments has made the issue particularly sensitive.

The episode has further escalated political tensions in the state, with security and accountability emerging as key points of debate.

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Himanta Biswa Sarma resigns as Assam chief minister, oath ceremony likely after May 11

Himanta Biswa Sarma resigns as Assam Chief Minister after BJP-led NDA’s victory. He will continue as caretaker CM until the new government is sworn in after May 11.

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Himanta sharma

Assam Chief Minister Himanta Biswa Sarma resigned from his post on Wednesday, paving the way for the formation of a new government after the BJP-led NDA secured a decisive victory in the 2026 Assembly elections.

Sarma submitted his resignation to Governor Lakshman Prasad Acharya at Lok Bhawan in Guwahati. The Governor accepted the resignation and asked him to continue as the caretaker Chief Minister until the new government takes charge.

The resignation comes after the NDA’s strong electoral performance, where the alliance won a clear majority in the 126-member Assembly, ensuring its return to power for another term.

Oath ceremony expected after May 11

Speaking to reporters after submitting his resignation, Sarma said the swearing-in ceremony for the new government is likely to be held after May 11.

He indicated that Prime Minister Narendra Modi has been invited to attend the ceremony but is unavailable until May 11, which has influenced the tentative schedule.

Decision on next chief minister soon

Sources suggest that central observers, including senior BJP leaders, are expected to arrive shortly to oversee the selection of the legislature party leader. The newly elected MLAs will then decide on the next Chief Minister.

Despite the formal resignation, party sources indicate that Sarma is likely to continue in the role for another term, given the BJP’s strong mandate in the state.

The move marks the beginning of the government formation process in Assam following the election results declared earlier this week.

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Rahul Gandhi and Vijay alliance took shape through backchannel talks, early signals from Congress leaders

Congress outreach and political calculations led to Rahul Gandhi and Vijay coming together after the Tamil Nadu 2026 election results.

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The coming together of Rahul Gandhi and actor-politician Vijay in Tamil Nadu after the 2026 Assembly elections was not sudden, but the result of behind-the-scenes political manoeuvring and early signals within the Congress.

According to media reports, some leaders in the Tamil Nadu Congress had already sensed the scale of Vijay’s surge during the campaign, anticipating what was later described as a “wave” in favour of his party.

After the results, where Vijay’s Tamilaga Vettri Kazhagam (TVK) emerged as the single largest party but fell short of a majority, communication channels between the Congress leadership and Vijay quickly became active.

A key moment in this evolving political equation was a phone call from Rahul Gandhi to Vijay, congratulating him on the party’s strong performance. The conversation was seen as more than a courtesy, signalling the possibility of cooperation at a time when government formation required additional support.

Reports indicate that discussions within Congress weighed the political benefits of supporting Vijay, especially given the shifting dynamics in the state where traditional dominance by major Dravidian parties has been challenged.

With TVK needing allies to cross the majority mark, Congress emerged as a potential partner, leading to a broader political realignment in the state. This development also triggered tensions within opposition alliances, highlighting the strategic importance of the decision.

The evolving partnership reflects a mix of electoral pragmatism and changing voter sentiment, particularly the growing influence of younger voters, which leaders acknowledged as a key factor in the election outcome.

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