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Correction pen is new tool to make cheap diagnostic kits

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Correction pen

[vc_row][vc_column][vc_column_text]By Sunderarajan Padmanabhan

The humble correction pen used to mask typos in printed or written text is all set to assume a new avatar. It could soon become an important component in fabrication of paper-based diagnostic kits.

Paper is becoming popular among experts in miniaturization and micro fluidics because of its ability to transport fluids through capillary action. It is also biodegradable, biocompatible and low cost. Using paper, scientists are developing analytical devices in association with fluorescence, colorimetric and electrochemical detection systems.

Its porosity makes paper easy to load a reagent needed for diagnostic tests. But the reagent needs to be confined to a specific area on the device using certain barriers. Normally such barriers can be fabricated using techniques like photolithography, flexography, plasma treatment, inkjet or screen printing. All these techniques require expert manpower and are time consuming.

                       

Researchers at the Indian Institute of Technology Kharagpur and Manipal Institute of Technology in Karnataka have now found that merely using a correction pen can help overcome the challenges associated with using paper in diagnostic tests. They have shown it is possible to fabricate paper-based devices by drawing out the confines for reagents with a normal correction pens.

“Even a novice can draw out the margins with a free-hand drawing. The device will work,” said Professor Suman Chakraborty of IIT Kharagpur, who led the research team. The correction pen contains titanium particles. When a line or a circle is drawn on a paper using correction pen, fine particles of titanium form barriers across channels on the paper, forming a confined space within which a reagent can be stored.

The scientists explored the possibility of developing a quantitative assay for blood glucose level – an important blood parameter. They tested 12 blood samples of varying glucose concentrations. Each sample was deposited in three different devices and the average colour intensities were measured. “All the reported data points agreed within 10% of the calibration curve”, researchers said.

“Our study may pave the way for developing a frugal titanium-based composites or inks for constructing paper-based device for bio-sensing applications compatible with the requirements of the economically deprived community at large, resulting in medical tests to be conducted with one drop of blood, urine or any other body fluid at phenomenally low costs”, Dr. Chakraborty added.

The team also included Naresh Mani, a visiting scholar from Manipal Institute of Technology and Sujay Kumar Viswas, a Ph.D student at IIT Kharagpur. The research results have been published in journal Scientific Reports. (India Science Wire)[/vc_column_text][/vc_column][/vc_row]

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PM Modi hails ISRO after successful GSLV-F17 launch, calls it proud moment

PM Modi congratulated ISRO after GSLV-F17 successfully launched EOS-05, calling the achievement a proud moment for India.

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Prime Minister Narendra Modi on Friday congratulated the Indian Space Research Organisation (ISRO) after the successful launch of the GSLV-F17 rocket carrying the EOS-05 Earth observation satellite, describing the achievement as a proud moment for the nation.

The GSLV-F17 lifted off at 2:55 a.m. IST from the Satish Dhawan Space Centre in Sriharikota, Andhra Pradesh. The EOS-05 satellite was subsequently placed into its designated sub-geosynchronous transfer orbit.

PM Modi praises ISRO’s growing capabilities

In a post on X, PM Modi said the successful mission reflected the excellence, innovation and expanding capabilities of India’s space sector.

He also highlighted the growing partnership between ISRO and Indian industry, saying it was strengthening India’s space programme and expanding capabilities across the wider space ecosystem.

The prime minister described the successful launch of GSLV-F17 carrying EOS-05 as another outstanding achievement by ISRO and a matter of national pride.

EOS-05 strengthens earth observation capabilities

According to the report, EOS-05 is India’s first-ever imaging satellite from geosynchronous orbit. The satellite is designed to provide continuous observation of the country from an altitude of nearly 36,000 km above Earth.

The mission is expected to strengthen India’s earth observation capabilities and support advanced imaging and observation applications.

ISRO Chairman Dr V Narayanan expressed satisfaction with the mission, saying the satellite was precisely injected into its intended orbit.

Mission Director Thomas Kurian described the launch as a significant milestone for the GSLV programme. He said it was the 19th flight of the GSLV and noted that EOS-05 is the heaviest satellite the launch vehicle has placed into a geosynchronous transfer orbit or sub-GTO orbit.

GSLV-F17 launch vehicle details

The GSLV-F17 stands 51.7 metres tall and has an approximate liftoff mass of 420.5 tonnes.

Science and Technology Minister Jitendra Singh also congratulated the ISRO team following the successful mission. He described EOS-05 as a state-of-the-art Earth observation satellite capable of advanced imaging across visible, infrared, multispectral and hyperspectral bands.

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Indian-origin astronaut Anil Menon begins first mission to International Space Station

Indian-origin NASA astronaut Anil Menon has launched aboard Soyuz MS-29 on his first mission to the International Space Station, where he is expected to spend around eight months conducting research.

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Indian-origin NASA astronaut Anil Menon has embarked on his first journey into space after successfully launching aboard Russia’s Soyuz MS-29 spacecraft to the International Space Station (ISS).

The mission lifted off from the historic Baikonur Cosmodrome in Kazakhstan at 8:17 PM on Tuesday. Menon was accompanied by Russian cosmonauts Pyotr Dubrov and Anna Kikina as the three-member crew began their expedition to the orbiting laboratory.

Crew to spend about eight months aboard ISS

The Soyuz MS-29 spacecraft is expected to dock with the International Space Station a little over three hours after launch. Once aboard the ISS, the crew will carry out a range of scientific research and technology demonstration projects during their mission.

The expedition is scheduled to last approximately eight months, with the crew expected to return to Earth in 2027 after completing their planned activities in orbit.

Menon’s maiden spaceflight marks a significant milestone in his astronaut career as he joins the International Space Station crew for long-duration research and operational work.

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Astronaut Shubhanshu Shukla to meet PM Modi after return from historic space mission

Astronaut Shubhanshu Shukla, who recently returned from the ISS as part of the Axiom-4 mission, will meet PM Modi this evening. Parliament will also hold a special discussion on his historic journey.

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Subhanshu shukla

Indian astronaut Group Captain Shubhanshu Shukla, the first Indian to visit the International Space Station (ISS), will meet Prime Minister Narendra Modi this evening at his official residence in New Delhi.

PM Modi to host meeting with astronaut

According to officials, the meeting at 7 Lok Kalyan Marg is expected to take place between 5 pm and 5:30 pm. Shukla, who arrived in India on Sunday, will also be part of the National Space Day celebrations scheduled for August 23.

Warm welcome in India

The astronaut was greeted at the airport by his family, Science and Technology Minister Jitendra Singh, Delhi Chief Minister Rekha Gupta, and hundreds of citizens waving the national flag. Shukla had been in the United States for a year, preparing for the Axiom-4 mission, which launched from Florida on June 25 and docked at the ISS the next day. He served as the mission’s pilot.

Emotional note from Shukla

Before his return, Shukla shared an emotional post on Instagram, expressing mixed feelings of leaving his space colleagues while being eager to meet his loved ones and people of India. He also quoted a song from the film Swades, which he had chosen as his anthem on the launch day.

Parliament session on India’s space journey

In honour of Shukla’s mission, the Lok Sabha is holding a special session today to discuss “India’s first astronaut aboard the ISS – critical role of space programme for Viksit Bharat by 2047.” Union minister Kiren Rijiju said the discussion would highlight the importance of India’s space achievements and future goals.

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