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New study suggests kidney disease may be linked to pesticide exposure

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New study suggests kidney disease may be linked to pesticide exposure

By Bhavya Khullar

Joint study by University College of Medical Sciences and Guru Teg Bahadur Hospital shows Chronic Kidney Disease patients had higher levels of three pesticides

New Delhi, September 7 (India Science Wire): Patients with chronic kidney disease have higher amounts of organochlorine pesticides in their body, a Delhi-based study has indicated.

Doctors at the University College of Medical Sciences and Guru Teg Bahadur Hospital in Delhi studied 300 individuals aged 30-54 years, who visited kidney clinic between January 2014 and March 2015. Their blood samples were tested for presence of a range of organochlorine pesticides – alpha and beta endosulphan, DDT and DDE, dieldrin, Aldrin, and alpha, beta, and gamma HCH.

“We found that Chronic Kidney Disease (CKD) patients had higher levels of three pesticides, beta-endosuplhan, aldrin, and alpha-HCH in their blood as compared to healthy people”, Ashok Kumar Tripathi, who led the research, told the India Science Wire. This, he said, suggested a possible involvement of pesticides with abnormal kidney function.

It was found that the median levels of alpha-HCH, beta-endosulphan, and aldrin in healthy subjects were 0.7, 1.38, and 1.6 parts per billion respectively. In patients of chronic kidney disease, these levels were significantly higher -1.68, 2.38, and 2.15 parts per billion respectively. The results were published recently in journal Environmental Health and Preventive Medicine.

Although the mechanism of how pesticides affect kidney health is yet to be elucidated, researchers believe that accumulated amounts of pesticides may induce oxidative stress in the kidneys, which leads to CKD. In order to confirm the link, follow up studies with a larger group of people are required, said Dr Tripathi.

Still the study is significant because it finds high levels of pesticides in people living in an urban area like Delhi – who are not directly involved in agricultural activity or manufacture of pesticides – and who probably got exposed through environmental contamination, pointed out Catharina Wesseling, toxicologist at the Central American Institute for Studies on Toxic Substances, Universidad Nacional in Costa Rica. She was not involved in the Delhi study.

Dr Wesseling told India Science Wire that, “while this study does not establish that pesticides cause kidney disease, it is known that many pesticides are toxic for the kidneys. One can expect to find associations between (some) pesticides and kidney dysfunction”.

Organochlorine pesticides such as DDT and endosulfan are banned in many countries owing to their long persistence in the environment and adverse impacts on human health. Previous studies from El Salvador, Central America, Mexico, and Sri Lanka have indicated their possible involvement in development of CKD. Chronic Kidney Disease affects nearly 17 percent of the Indian population and is expected to rise with increasing cases of hypertension and diabetes.

The research team included Rishila Ghosh, Manushi Siddarth, Neeru Singh, Vipin Tyagi, Pawan Kumar Kare, Basu Dev Banerjee, Om Prakash Kalra, and Ashok Kumar Tripathi. This study was funded by the Department of Science and Technology (DST-SERB).

(This is an article from a syndicated feed provided by the Indian Science Wire)

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Indian-origin astronaut Anil Menon begins first mission to International Space Station

Indian-origin NASA astronaut Anil Menon has launched aboard Soyuz MS-29 on his first mission to the International Space Station, where he is expected to spend around eight months conducting research.

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Indian-origin NASA astronaut Anil Menon has embarked on his first journey into space after successfully launching aboard Russia’s Soyuz MS-29 spacecraft to the International Space Station (ISS).

The mission lifted off from the historic Baikonur Cosmodrome in Kazakhstan at 8:17 PM on Tuesday. Menon was accompanied by Russian cosmonauts Pyotr Dubrov and Anna Kikina as the three-member crew began their expedition to the orbiting laboratory.

Crew to spend about eight months aboard ISS

The Soyuz MS-29 spacecraft is expected to dock with the International Space Station a little over three hours after launch. Once aboard the ISS, the crew will carry out a range of scientific research and technology demonstration projects during their mission.

The expedition is scheduled to last approximately eight months, with the crew expected to return to Earth in 2027 after completing their planned activities in orbit.

Menon’s maiden spaceflight marks a significant milestone in his astronaut career as he joins the International Space Station crew for long-duration research and operational work.

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Astronaut Shubhanshu Shukla to meet PM Modi after return from historic space mission

Astronaut Shubhanshu Shukla, who recently returned from the ISS as part of the Axiom-4 mission, will meet PM Modi this evening. Parliament will also hold a special discussion on his historic journey.

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Subhanshu shukla

Indian astronaut Group Captain Shubhanshu Shukla, the first Indian to visit the International Space Station (ISS), will meet Prime Minister Narendra Modi this evening at his official residence in New Delhi.

PM Modi to host meeting with astronaut

According to officials, the meeting at 7 Lok Kalyan Marg is expected to take place between 5 pm and 5:30 pm. Shukla, who arrived in India on Sunday, will also be part of the National Space Day celebrations scheduled for August 23.

Warm welcome in India

The astronaut was greeted at the airport by his family, Science and Technology Minister Jitendra Singh, Delhi Chief Minister Rekha Gupta, and hundreds of citizens waving the national flag. Shukla had been in the United States for a year, preparing for the Axiom-4 mission, which launched from Florida on June 25 and docked at the ISS the next day. He served as the mission’s pilot.

Emotional note from Shukla

Before his return, Shukla shared an emotional post on Instagram, expressing mixed feelings of leaving his space colleagues while being eager to meet his loved ones and people of India. He also quoted a song from the film Swades, which he had chosen as his anthem on the launch day.

Parliament session on India’s space journey

In honour of Shukla’s mission, the Lok Sabha is holding a special session today to discuss “India’s first astronaut aboard the ISS – critical role of space programme for Viksit Bharat by 2047.” Union minister Kiren Rijiju said the discussion would highlight the importance of India’s space achievements and future goals.

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Shubhanshu Shukla pens emotional note as he returns to India after space mission

Indian astronaut Shubhanshu Shukla penned an emotional Instagram post as he returned to India after his 18-day ISS mission, marking a milestone in India’s space journey.

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Indian astronaut Group Captain Shubhanshu Shukla has shared an emotional Instagram post as he heads back home after completing his 18-day mission aboard the International Space Station (ISS).

Astronaut reflects on mixed emotions

In his heartfelt message, written from the aircraft, Shukla expressed the whirlwind of emotions he felt while leaving behind his fellow astronauts, who had been his family during the mission. “As I sit on the plane to come back to India, I have a mix of emotions running through my heart. I feel sad leaving a fantastic group of people behind who were my friends and family for the past year during this mission. I am also excited about meeting all my friends, family and everyone in the country for the first time post mission. I guess this is what life is — everything all at once,” he wrote.

Acknowledges support and inspiration

The astronaut thanked everyone for the love and support he received throughout his journey. He also recalled the words of his commander Peggy Whitson, saying, “Goodbyes are hard, but we need to keep moving in life. As my commander Peggy Whitson fondly says, ‘The only constant in spaceflight is change’. I believe that applies to life as well.”

Shukla ended his note with a line from the song Yun Hi Chala Chal from the film Swades, reflecting his spirit of resilience.

Link to India’s space ambitions

Shukla’s return comes at a crucial time as India advances its space programme. Prime Minister Narendra Modi had earlier mentioned that the astronaut would soon return and that he was tasked with documenting his training and ISS stay. This record will serve as a valuable reference for Gaganyaan, India’s first human spaceflight mission.

Over the past year, Shukla trained extensively at NASA, Axiom, and SpaceX facilities. His flight to the ISS as part of the Axiom 4 mission marked a milestone in India’s preparations for future human space exploration.

The Gaganyaan project aims to send Indian astronauts into orbit aboard an indigenous rocket. The government has also outlined plans for a Bharatiya Antariksh Station by 2035 and a crewed mission to the moon by 2040.

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