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COVID VACCINE DEVELOPMENT RACE HOTS UP

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American drugmaker Pfizer Inc, which had partnered with German biotech firm BioNTech to develop a vaccine candidate against Covid-19 earlier this year, has become the latest in the list of major movers in the vaccine race to move into the final stages of human trials. Right on the heels of Moderna Therapeutics, Pfizer announced that its vaccine candidate, called BNT162b2 for the time being, has progressed to phase II/III trials.

Like Moderna, Pfizer’s candidate belongs to a category called a messenger RNA vaccine. These types of vaccines involve modifying a messenger RNA to get the cells to recreate the part of the virus that is crucial to target. In this case, the Pfizer-BioNTech vaccine has modified the messenger RNA to instruct the cells in the body to produce the spiky outer surface of the SARS-CoV-2 virus–the spike glycoprotein.

The latest development means that Pfizer will be conducting two stages of clinical trials seamlessly, an approach that intends to shorten the time taken to conduct these tests. The trials will check for the safety and effectiveness of the vaccine in persons between the ages of 18 to 85 years and will be conducted not only in the US, but in 120 sites globally. The duo is targeting 39 states across the US, as well as countries like Argentina, Brazil and Germany.

Coronavirus

Before this, Pfizer-BioNTech had conducted early stage phase I/II trials in the US and Germany. If the late stage trials succeed in showing that the candidate is effective in preventing a person from getting Covid-19, Pfizer and BioNTech will be “on track” to approaching the American drug regulator for approvals as early as October this year.

If approval is given, the firm plans to supply up to 100 million doses by the end of 2020 and around 1.3 billion doses by the end of 2021. BNT162b2 is one of four candidates that Pfizer and BioNTech were investigating as potential vaccines to protect people from getting Covid-19.

Both Bharat Biotech and Cadila are testing one another candidate. Bharat Biotech has joined hands with Thomas Jefferson University in Philadelphia, United States for this other candidate vaccine. It is being developed at the university facilities.

Read Also: COVID VACCINE DEVELOPMENT RACE HOTS UP

Besides these two, Pune-based Serum Institute of India is collaborating with Codagenix, a biotechnology company in New York, to develop a Coronavirus vaccine. Indian Immunologicals Limited, a public-sector company in Hyderabad which produces several animal and human vaccines, is working with Griffith University of Australia to develop a vaccine.

Cadila’s other vaccine is of a different type than the one which has gone into human trials.

India News

West Bengal Governor dissolves Assembly amid political transition 

Governor R N Ravi dissolved the West Bengal Assembly after the 2026 poll results, with the BJP securing a majority in the state elections.

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The West Bengal Legislative Assembly was dissolved following the conclusion of the 2026 Assembly elections, in which the Bharatiya Janata Party secured a clear majority in the state.

Governor R N Ravi issued the order dissolving the Assembly as the state prepared for the transition of power after the election results. According to reports, the BJP won 207 seats in the 294-member Assembly, while the Trinamool Congress secured 80 seats.

Chief Minister Mamata Banerjee questioned the election outcome and alleged irregularities in the poll process, claiming the mandate had been “looted”.

The dissolution came as the tenure of the existing Assembly ended on May 7, 2026. The development has sparked political discussions over the formation of the next government in the state.

Meanwhile, Mamata Banerjee held a meeting with newly elected Trinamool Congress MLAs in Kolkata and reportedly raised concerns over internal sabotage during the elections.

The BJP is expected to begin the formal process of government formation in West Bengal after its decisive victory in the Assembly polls.

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Eknath Shinde’s helicopter returns to Mumbai mid-flight due to bad weather

Maharashtra Deputy Chief Minister Eknath Shinde’s helicopter was forced to return to Mumbai after the pilot detected approaching storm conditions during a flight to Thane district.

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A helicopter carrying Maharashtra Deputy Chief Minister Eknath Shinde was forced to return to Mumbai on Thursday after encountering adverse weather conditions during a flight to Thane district.

According to officials, Shinde had departed from Mahalaxmi Racecourse in south Mumbai around 3.30 pm and was travelling to Murbad in Thane district to attend a wedding function related to a party worker’s family.

The helicopter reportedly reached the Airoli area in Navi Mumbai when the pilot noticed an approaching storm and informed the deputy chief minister about the deteriorating weather conditions. Following the alert, the flight was turned back as a precautionary measure.

The helicopter later landed safely at the Pawan Hans facility in Juhu, Mumbai. Officials said Shinde was accompanied by members of his staff, including personal assistant Prabhakar Kale, special executive officer Balsingh Rajput and media adviser Vinay Patrdukar.

The incident comes amid changing weather conditions and storm activity reported in parts of Maharashtra in recent days.

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Nitish Kumar’s son Nishant among 32 inducted in Bihar cabinet expansion

Nishant Kumar entered the Bihar cabinet for the first time as 32 ministers from NDA allies took oath in a major expansion of the state government.

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Bihar government cabinet

A major cabinet expansion took place in Bihar on Thursday, with 32 leaders from the ruling NDA alliance inducted into the state government. Among the prominent names was Nishant Kumar, son of former Bihar chief minister Nitish Kumar, who entered the cabinet for the first time.

The expansion included representatives from all major NDA allies in the state. According to reports, the BJP secured 15 ministerial berths, while JD(U) got 13 positions. Two ministers were inducted from Lok Janshakti Party (Ram Vilas), while Hindustani Awam Morcha and Rashtriya Lok Morcha received one berth each.

The oath-taking ceremony was held in Patna in the presence of senior NDA leaders, including Prime Minister Narendra Modi, Union Home Minister Amit Shah and Defence Minister Rajnath Singh.

Nishant Kumar’s induction comes weeks after he formally entered active politics. His entry into the Bihar cabinet is being viewed as a significant development for JD(U), which had long projected an anti-dynasty image under Nitish Kumar’s leadership.

The cabinet reshuffle follows Nitish Kumar’s move to the Rajya Sabha earlier this year and the formation of the government led by Chief Minister Samrat Choudhary.

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