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SEARCH FOR COVID 19 VACCINE CONTINES.

Moderna Inc, which is one of the frontrunners in the global hunt for a vaccine development surpassed a crucial stage of the clinical trials. The pharmaceutical giant, which is set to conduct stage-3 trials of its novel mRNA-1273 vaccine in July has said that preliminary studies suggest that one dose of the vaccine may be able to nip the infection and may not pose any serious health adversaries.

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Moderna Inc, which is one of the frontrunners in the global hunt for a vaccine development surpassed a crucial stage of the clinical trials. The pharmaceutical giant, which is set to conduct stage-3 trials of its novel mRNA-1273 vaccine in July has said that preliminary studies suggest that one dose of the vaccine may be able to nip the infection and may not pose any serious health adversaries. A series of studies conducted on mice found that the vaccine may effectively work garner protection against COVID-19.

The vaccine, which is currently in its second phase of testing is likely to proceed ahead with the third phase of clinical trials, where it plans to involve about 30,000 participants between the ages of 18-55 and those who are at high risk for COVID-19. If all goes well, the company has promised to produce over 100 million doses of its innovative vaccine before the year ends.

In a more promising news coming out of India, a Delhi-based biotechnology company, Panacea Biotec Limited signed a partnership with a US-based pharma company, Refana Inc to develop, manufacture and distribute an experimental COVID-19 vaccine which is currently in the works.

The vaccine prototype, which will make use of an inactivated virus strain has shown effective results in the pre-clinical trials conducted in the US. Toxicology studies and animal trials will be conducted in labs across Delhi and Punjab, following which, the company aims to proceed to human trials in the month of October. Apart from Panacea, there are seven other Indian companies in the league to find a vaccine for COVID-19.

Out of the five vaccine candidates being produced in China, Beijing-based Sinovac Biotech Ltd, which is producing a novel vaccine called CoroVac has said that the vaccine has shown largely positive results on 90% of people being tested in the clinical trials.

The pharma giant went on to say that the vaccine prototype was administered to patients for a 14-day period, following which, more than 90% of people went on to develop neutralizing antibodies after injection.

A vaccine being jointly developed by Oxford University and British-Swedish pharma company AstraZeneca have also been given approvals to conduct stage-3 trials in the country, which is now one of the worst affected nations by the pandemic.

American firm, Johnson and Johnson who is also amongst the 110 groups in contention of vaccine development announced that it was fast-tracking human clinical trials for its innovative recombinant vaccine, which was to be earlier held in the month of September. The trials, which will now be held in July were decided after pre-clinical trials and studies showed promising results.

According to reports, the first stage of trials will involve 1035 healthy participants aged between 18 and 55 based out of the US and Belgium. The company has also sought permission from regulatory boards to start large scale human trials ahead of schedule.

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President’s Rule revoked in Manipur as NDA set to form new government

President’s Rule has been withdrawn in Manipur nearly a year after its imposition, paving the way for a new NDA-led government under Yumnam Khemchand Singh.

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President rule invoked in Manipur

President’s Rule has been revoked in Manipur nearly a year after it was imposed, clearing the way for the formation of a new government led by the BJP-led National Democratic Alliance (NDA). The decision came hours before the scheduled oath ceremony of the new council of ministers.

Chief minister-designate Yumnam Khemchand Singh is set to take oath later this evening, along with other NDA legislators who will formally join the new government. The revocation brings an end to central rule that had been in place since February 2025, following the resignation of then chief minister N Biren Singh.

Assembly status during central rule

During the period of President’s Rule, the Manipur Legislative Assembly remained in suspended animation, meaning it was neither functioning nor dissolved. With the restoration of the elected government, legislative activity is expected to resume.

Khemchand Singh, 61, belongs to the Meitei community. Two deputy chief ministers have been named to reflect Manipur’s ethnic diversity. Nemcha Kipgen, from the Kuki community, and Losii Dikho, from the Naga community, are set to take charge as deputy chief ministers.

According to people with direct knowledge of the matter, Nemcha Kipgen is likely to take oath from a Manipur government guesthouse in Delhi.

Key portfolios and leadership choices

Seven-time MLA from Bishnupur district, Govindas Konthoujam, said he has been entrusted with the Home portfolio. Emphasising stability and law and order, he said he remains committed to serving the state with discipline and restraint.

Sources said Khemchand Singh is viewed within the party as a non-polarising leader who is acceptable across internal factions at a time of political transition. While he is yet to be tested in governance, he is seen as a steady administrative choice capable of providing organisational discipline and continuity amid uncertainty.

Uneasy peace continues in Manipur

The formation of the new government comes against the backdrop of continued tension in Manipur, nearly three years after violence erupted between the Meitei community in the valley areas and the Kuki tribes in several hill districts.

A section of Kuki groups has been demanding a separate administrative arrangement, with negotiations involving multiple insurgent groups operating under two umbrella organisations that are signatories to the suspension of operations agreement.

In recent weeks, some Kuki civil society organisations have stated they would not participate in the Manipur government and have distanced themselves from Kuki MLAs expected to join the new administration.

A day before the announcement of the new government, Kuki leader Paolienlal Haokip posted on X that representatives of the Kuki Zo people could not take part in leadership selection without justice and a written commitment for political settlement.

Diverging demands from communities

Meitei civil society groups have maintained that all internally displaced persons should be allowed to return home safely, even as dialogue continues. However, Kuki leaders have insisted that a political solution in the form of a separate administration must come first, before discussions on rehabilitation and return from relief camps.

Meitei leaders have countered this position, arguing that the demand reflects an ethnocentric territorial claim and that humanitarian issues should be addressed alongside negotiations, as no area is exclusively inhabited by a single community.

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BJP spokesperson Shehzad Poonawalla’s mother injured in hit-and-run incident in Pune

BJP spokesperson Shehzad Poonawalla has alleged that his mother was deliberately hit by a car in Pune and left critically injured. She is scheduled to undergo surgery.

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Shehzad Punawalla

BJP national spokesperson Shehzad Poonawalla has claimed that his mother was seriously injured after being struck by a car in an alleged hit-and-run incident in Pune. The accused reportedly fled the spot after the incident, leaving her critically injured.

According to Poonawalla, the incident occurred a few hours earlier and his mother is scheduled to undergo surgery. He appealed to authorities to identify and arrest the person responsible at the earliest.

Sharing details on social media, Poonawalla said an unidentified individual ran a car over his mother and escaped from the scene. He requested prayers for her recovery and expressed anguish over the incident, describing his mother as a compassionate person whose injury had deeply shaken him.

He also tagged Pune City Police, senior police officials, and Maharashtra Chief Minister Devendra Fadnavis, urging strict legal action against the accused and ensuring that the person does not evade accountability.

CCTV footage surfaces, police complaint to be filed

In a related development, Poonawalla’s brother and political analyst Tehseen Poonawalla shared CCTV footage on social media that allegedly shows the moment their mother was hit by the vehicle.

Tehseen stated that his mother, a senior citizen, had stepped out of the car while it was being refuelled when the incident occurred. He alleged that the act appeared deliberate and said efforts were underway to identify the vehicle involved.

He further confirmed that a police complaint would be filed and questioned how the vehicle could have hit his mother when she was standing at a distance from the car.

Fractured hip, surgery planned

Providing an update on her medical condition, Tehseen said their mother had suffered a fractured hip and would require surgical intervention. She has been admitted to hospital and doctors are monitoring her vitals ahead of surgery.

He described the incident as infuriating and heartbreaking, adding that his mother would need a rod implant following the hip surgery. He also said he had spoken to senior police officials and expressed hope that swift action would be taken.

Authorities have not yet issued an official statement on the incident. Further details are awaited as investigations continue.

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Three sisters die after jumping from ninth floor in Ghaziabad

Three minor sisters died after jumping from the ninth floor of their Ghaziabad apartment, allegedly following a dispute over online gaming, police said.

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Three sisters die after jumping from ninth floor in Ghaziabad

Three minor sisters died after jumping from the ninth floor of their apartment building in Uttar Pradesh’s Ghaziabad, allegedly following objections by their parents to their online gaming habits.

The incident occurred at Bharat City, a residential township in Ghaziabad, at around 2 am on Wednesday. The girls were found dead at the spot.

The sisters have been identified as Pakhi, aged 12, Prachi, 14, and Vishika, 16.

According to police, the three siblings were extremely close and spent most of their time together. They reportedly followed the same daily routine, including bathing, eating, attending school, and sleeping together.

Preliminary findings suggest the girls had become addicted to online gaming during the COVID-19 pandemic. They were reportedly playing an online task-based game referred to as a ‘Korean love game’. Police also said the sisters were not attending school regularly.

Investigators said the parents had objected to the girls’ excessive gaming, following which the incident allegedly took place. Police teams reached the spot soon after and have begun an investigation to ascertain the exact sequence of events.

Further details are awaited as the probe continues.

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