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SEARCH FOR COVID 19 VACCINE CONTINES.

Moderna Inc, which is one of the frontrunners in the global hunt for a vaccine development surpassed a crucial stage of the clinical trials. The pharmaceutical giant, which is set to conduct stage-3 trials of its novel mRNA-1273 vaccine in July has said that preliminary studies suggest that one dose of the vaccine may be able to nip the infection and may not pose any serious health adversaries.

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Moderna Inc, which is one of the frontrunners in the global hunt for a vaccine development surpassed a crucial stage of the clinical trials. The pharmaceutical giant, which is set to conduct stage-3 trials of its novel mRNA-1273 vaccine in July has said that preliminary studies suggest that one dose of the vaccine may be able to nip the infection and may not pose any serious health adversaries. A series of studies conducted on mice found that the vaccine may effectively work garner protection against COVID-19.

The vaccine, which is currently in its second phase of testing is likely to proceed ahead with the third phase of clinical trials, where it plans to involve about 30,000 participants between the ages of 18-55 and those who are at high risk for COVID-19. If all goes well, the company has promised to produce over 100 million doses of its innovative vaccine before the year ends.

In a more promising news coming out of India, a Delhi-based biotechnology company, Panacea Biotec Limited signed a partnership with a US-based pharma company, Refana Inc to develop, manufacture and distribute an experimental COVID-19 vaccine which is currently in the works.

The vaccine prototype, which will make use of an inactivated virus strain has shown effective results in the pre-clinical trials conducted in the US. Toxicology studies and animal trials will be conducted in labs across Delhi and Punjab, following which, the company aims to proceed to human trials in the month of October. Apart from Panacea, there are seven other Indian companies in the league to find a vaccine for COVID-19.

Out of the five vaccine candidates being produced in China, Beijing-based Sinovac Biotech Ltd, which is producing a novel vaccine called CoroVac has said that the vaccine has shown largely positive results on 90% of people being tested in the clinical trials.

The pharma giant went on to say that the vaccine prototype was administered to patients for a 14-day period, following which, more than 90% of people went on to develop neutralizing antibodies after injection.

A vaccine being jointly developed by Oxford University and British-Swedish pharma company AstraZeneca have also been given approvals to conduct stage-3 trials in the country, which is now one of the worst affected nations by the pandemic.

American firm, Johnson and Johnson who is also amongst the 110 groups in contention of vaccine development announced that it was fast-tracking human clinical trials for its innovative recombinant vaccine, which was to be earlier held in the month of September. The trials, which will now be held in July were decided after pre-clinical trials and studies showed promising results.

According to reports, the first stage of trials will involve 1035 healthy participants aged between 18 and 55 based out of the US and Belgium. The company has also sought permission from regulatory boards to start large scale human trials ahead of schedule.

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Tamil Nadu potboiler: Now, Sasikala to launch new party ahead of election

Sasikala has announced the launch of a new political party ahead of the Tamil Nadu Assembly elections, positioning herself against AIADMK chief Edappadi K Palaniswami.

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In a significant political development ahead of the Tamil Nadu Assembly elections, expelled AIADMK leader V. K. Sasikala has announced that she will float a new political party and contest the polls by fielding her own candidates.

Speaking in Madurai before heading to Pasumpon for a public event, Sasikala said she would unveil her party’s flag later in the evening. She indicated that more details regarding the party’s structure and plans would be shared at the gathering.

The event venue carries political symbolism. Pasumpon is the birthplace of Thevar leader Muthuramalinga Thevar, and Sasikala herself belongs to the influential Thevar community in southern Tamil Nadu. The programme was held as part of birth anniversary events of former Chief Minister J. Jayalalithaa.

Direct challenge to EPS

Sasikala’s move is being viewed as a direct political challenge to AIADMK general secretary Edappadi K. Palaniswami (EPS). After Jayalalithaa’s death in 2016, Sasikala briefly took control of the party and had appointed Palaniswami as Chief Minister. However, following her conviction in the disproportionate assets case, she served a four-year prison term, and during that period, she was expelled from the party.

Palaniswami later aligned with O. Panneerselvam, whom Sasikala had earlier removed from the Chief Minister’s post. The two leaders subsequently adopted a dual leadership arrangement within the party and government.

Sasikala remains disqualified from contesting elections until 2027 due to her conviction. Nevertheless, she has stated that she intends to field candidates under her new party banner.

Fragmented Thevar vote base

Over the years, expulsions within the AIADMK — including Sasikala, her nephew TTV Dhinakaran and O Panneerselvam — have led to divisions within the Thevar support base. Political observers have linked this fragmentation to the party’s weakened electoral performance in the elections following Jayalalithaa’s passing.

While Dhinakaran has returned to the NDA fold, reports suggest Palaniswami is opposed to any arrangement that includes Sasikala or Panneerselvam. OPS, meanwhile, has exited the NDA.

Sasikala has repeatedly criticised Palaniswami, describing him as a betrayer, while he maintains that his leadership stems from the support of AIADMK legislators rather than her backing.

The AIADMK has not issued an official statement on Sasikala’s announcement. However, a senior party leader questioned her political standing, pointing out her disqualification from contesting elections and referring to legal issues linked to Jayalalithaa’s death.

With the Assembly polls approaching, Sasikala’s re-entry into active politics could further complicate the opposition space in Tamil Nadu and influence electoral calculations, particularly in the southern districts.

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As stealth reshapes air combat, India weighs induction of Sukhoi Su-57 jets

India is assessing the possible induction of up to 40 Sukhoi Su-57 fifth-generation fighter jets as stealth becomes central to future air combat strategy.

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Sukhoi Su-57 jets

Aerial warfare is increasingly being defined by the ability to remain undetected rather than by traditional dogfighting skills, and India is now assessing options to strengthen its capabilities in this new paradigm. Defence circles are abuzz with indications that the Indian Air Force may consider procuring up to 40 Russian fifth-generation Su-57 fighter jets, according to sources.

The possible move comes less than a year after Operation Sindoor, which was launched in May last year following the Pahalgam terror attack. The air engagements with the Pakistan Air Force during the operation are understood to have provided fresh operational insights, prompting discussions on future preparedness.

Why stealth is central to fifth-generation fighters

Fifth-generation fighter aircraft are designed with a strong emphasis on low observability. Platforms such as the Su-57 incorporate airframes shaped to reduce radar signatures and use radar-absorbent materials to make detection more difficult across radar, infrared and visible spectrums.

These aircraft typically integrate advanced avionics, sensor fusion and supercruise capabilities. They are also configured to carry specialised weapons internally, enhancing stealth during combat missions.

According to information available on Sukhoi’s official platform, the Su-57 is equipped with a deeply integrated avionics suite that offers a high level of automation and intelligent crew support. Its onboard systems enable it to operate autonomously and exchange data in real time with ground control systems or as part of a coordinated task force.

The aircraft can deploy a broad range of air-to-air and air-to-surface munitions, allowing it to undertake both fighter and strike roles. Sukhoi states that the jet is capable of conducting covert missions owing to reduced visibility across multiple wavelength ranges.

The Su-57 is also fitted with an auxiliary power unit designed to improve deployment autonomy and lower fuel consumption during ground operations. An onboard oxygen extraction unit enhances operational endurance. Additionally, the aircraft features an explosion-proof fuel tank system described as a generator-type neutral gas system, aimed at improving combat survivability.

Regional security context

The reported deliberations come amid evolving regional dynamics. China, regarded as Pakistan’s close strategic partner, has developed the J-20 fifth-generation stealth fighter, and there are indications that such capabilities could eventually be shared with Pakistan.

India is also pursuing its own fifth-generation programme, the Advanced Medium Combat Aircraft (AMCA). The first flight of the AMCA is expected around 2028 or 2029, with induction into the Air Force projected around 2035.

In this backdrop, any decision on the Su-57 would form part of a broader effort to ensure that the Indian Air Force remains prepared for future aerial warfare scenarios where stealth and advanced sensing capabilities play a decisive role.

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RSS chief backs nationwide rollout of Uniform Civil Code, cites Uttarakhand model

RSS chief Mohan Bhagwat has supported nationwide implementation of the Uniform Civil Code, urging adoption of the Uttarakhand model.

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Mohan Bhagwat

Rashtriya Swayamsevak Sangh chief Mohan Bhagwat has expressed support for implementing the Uniform Civil Code (UCC) across the country, stating that it would be a “very good thing” if adopted nationwide. He suggested that the framework introduced in Uttarakhand could serve as a model for other states.

Speaking at a former servicemen’s dialogue seminar organised to mark the RSS’s 100th anniversary, Bhagwat said the UCC should be implemented in a manner similar to the approach followed by Uttarakhand. The hill state became the first in the country to enforce the Uniform Civil Code on January 27 last year.

Highlighting the process adopted in Uttarakhand, Bhagwat noted that after a draft proposal was prepared, it was opened for public discussion. According to him, suggestions from nearly three lakh people were received, and these inputs were examined and incorporated.

Describing the UCC as essential for societal unity, the RSS chief said such a legal framework would strengthen social cohesion.

When asked about the ongoing issue concerning the University Grants Commission, Bhagwat declined to comment, stating that the matter is currently under consideration by the Supreme Court of India.

Addressing retired personnel from the armed forces and paramilitary services at the event, Bhagwat underlined the continuing importance of defence forces, even in an independent nation, to safeguard sovereignty.

He also reflected on the journey of the RSS, saying the organisation was established without external resources and continued to grow despite facing severe sanctions on two occasions. He attributed its progress to the confidence and support of society.

Encouraging participation, Bhagwat invited former servicemen to attend Sangh camps and programmes to observe the work of volunteers and contribute to service activities based on their interests and abilities.

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