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RACE FOR VACCINE DEVELOPMENT

American drugmaker Pfizer Inc, which had partnered with German biotech firm BioNTech to develop a vaccine candidate against Covid-19 earlier this year, has become the latest in the list of major movers in the vaccine race to move into the final stages of human trials.

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Covid-19 Vaccine Race

American drugmaker Pfizer Inc, which had partnered with German biotech firm BioNTech to develop a vaccine candidate against Covid-19 earlier this year, has become the latest in the list of major movers in the vaccine race to move into the final stages of human trials. Right on the heels of Moderna Therapeutics, Pfizer announced that its vaccine candidate, called BNT162b2 for the time being, has progressed to phase II/III trials.

Like Moderna, Pfizer’s candidate belongs to a category called a messenger RNA vaccine. These types of vaccines Finvolve modifying a messenger RNA to get the cells to recreate the part of the virus that is crucial to target. In this case, the Pfizer-BioNTech vaccine has modified the messenger RNA to instruct the cells in the body to produce the spiky outer surface of the SARS-CoV-2 virus–the spike glycoprotein.

The latest development means that Pfizer will be conducting two stages of clinical trials seamlessly, an approach that intends to shorten the time taken to conduct these tests

The trials will check for the safety and effectiveness of the vaccine in persons between the ages of 18 to 85 years and will be conducted not only in the US, but in 120 sites globally. The duo is targeting 39 states across the US, as well as countries like Argentina, Brazil and Germany.

corona VACCINE

Before this, Pfizer-BioNTech had conducted early stage phase I/II trials in the US and Germany.

If the late stage trials succeed in showing that the candidate is effective in preventing a person from getting Covid-19, Pfizer and BioNTech will be “on track” to approaching the American drug regulator for approvals as early as October this year.

If approval is given, the firm plans to supply up to 100 million doses by the end of 2020 and around 1.3 billion doses by the end of 2021.

BNT162b2 is one of four candidates that Pfizer and BioNTech were investigating as potential vaccines to protect people from getting Covid-19.

Both Bharat Biotech and Cadila are testing one another candidate. Bharat Biotech has joined hands with Thomas Jefferson University in Philadelphia, United States for this other candidate vaccine. It is being developed at the university facilities.

Besides these two, Pune-based Serum Institute of India is collaborating with Codagenix, a biotechnology company in New York, to develop a Coronavirus vaccine. Indian Immunologicals Limited, a public-sector company in Hyderabad which produces several animal and human vaccines, is working with Griffith University of Australia to develop a vaccine.

Read Rlso: COVID VACCINE DEVELOPMENT RACE HOTS UP

Cadila’s other vaccine is of a different type than the one which has gone into human trials.

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Samsung Galaxy S25 Ultra and iPhone 16 Pro Max: A comparative look at prices and specs in India

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Samsung Galaxy S25 Ultra with car crash detection feature

Samsung has introduced its latest high-end flagship, the Galaxy S25 Ultra, in India, igniting a new chapter in its ongoing rivalry with Apple’s iPhone 16 Pro Max. Both phones represent the pinnacle of smartphone technology, but they come at distinct price points and offer different specifications that cater to various user preferences.

Price comparison in India

The Galaxy S25 Ultra is available in three variants: the base model with 256GB of storage is priced at Rs 1,29,999; the 512GB model at Rs 1,49,999; and the 1TB version at Rs 1,65,999. These variants are offered in four color options: Titanium Silver Blue, Titanium Gray, Titanium White, and Titanium Black.

In contrast, the iPhone 16 Pro Max starts at Rs 1,44,900 for the 256GB model, with the 512GB and 1TB versions priced at Rs 1,64,900 and Rs 1,84,900, respectively. Samsung’s offerings are notably less expensive across similar storage options, with the 1TB model being nearly Rs 19,000 cheaper than its Apple counterpart.

Specifications face-off

The Samsung Galaxy S25 Ultra boasts a 6.9-inch display, slightly larger than its predecessor, and features a more contemporary design with rounded edges. Despite its larger size, it maintains a lightweight feel at only 218 grams and includes a robust 5,000mAh battery. The camera setup has been significantly upgraded, featuring a 200-megapixel primary sensor paired with a 50-megapixel ultra-wide and a 50-megapixel telephoto lens. It is powered by the Snapdragon 8 Elite for Galaxy, enhancing both efficiency and performance.

The iPhone 16 Pro Max, also with a 6.9-inch display, utilizes Apple’s Super Retina XDR technology with Always-On and ProMotion features for a superior viewing experience. It includes a new gold color option and a novel Camera Control button, adding functionality exclusive to the Pro models. The device is equipped with the A18 Pro chipset and features a redesigned camera system with a 48-megapixel primary sensor and advanced video recording capabilities.

Performance and functionality

Both the Galaxy S25 Ultra and the iPhone 16 Pro Max are designed to offer top-tier performance. Samsung’s flagship includes 12GB of RAM, compared to the iPhone’s 8GB, potentially offering a smoother multitasking experience. The iPhone, however, continues to impress with its integration of hardware and software, leading to efficient performance in real-life usage scenarios.

This detailed examination highlights the strengths of each device, allowing consumers to make an informed decision based on their specific needs and preferences. Whether prioritizing camera technology, display features, or price, the Samsung Galaxy S25 Ultra and iPhone 16 Pro Max cater to all facets of premium smartphone requirements.

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Oppo Find N5 set to launch with 50W wireless charging and IPX9 water resistance

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Oppo Find N5 being tested underwater to showcase its IPX9 water resistance rating.

Oppo has officially confirmed that its latest innovation, the Find N5, will support 50W wireless charging and feature an IPX9 water resistance rating. The announcement comes as part of a series of teases highlighting the capabilities of this next-generation foldable smartphone, set to launch in February.

According to recent leaks, the Find N5 will be the first smartphone to incorporate the Qualcomm Snapdragon 8 Elite SoC, signaling significant performance enhancements. Pete Lau, Oppo’s Chief Product Officer, has touted the device as the “thinnest foldable phone,” positioning it against leading competitors like the latest iPhone in terms of sleek design.

Zhou Yibao, head of the Oppo Find series, shared insights via Weibo about the Find N5’s advanced features. The device not only matches the wireless charging speeds of newly released models like the Oppo Find X8 Pro and OnePlus 13 but also integrates seamlessly with in-car systems from major electric vehicle brands such as BYD and NIO.

In a compelling demonstration of its durability, a recent video posted by Yibao showed the Find N5 being submerged underwater, showcasing its capability to withstand significant water exposure, evidenced by its IPX9 rating. This test included recording underwater videos, highlighting the phone’s versatile camera capabilities in extreme conditions.

The Find N5 also sports a refined design with slimmer borders and a larger overall form factor compared to its predecessors, which could attract users looking for a sleek yet robust foldable phone.

As anticipation builds, Oppo has begun sharing images of the Find N5, revealing a foldable design as thin as a USB-C port when opened. This device promises to merge aesthetic appeal with functional excellence, setting a new benchmark in the evolving foldable phone market.

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Realme 14 Pro series set to launch in India tomorrow: Expected specs, price, and more

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Realme 14 Pro series launch with AMOLED display, Snapdragon 7s Gen 3 processor, and advanced camera setup.

Realme is gearing up to unveil its latest mid-range smartphones, the Realme 14 Pro series, in India on January 16, 2025. The much-anticipated event will also mark the launch of Realme Buds 5 wireless earphones, adding to the excitement among tech enthusiasts.

When and where to watch the launch

The Realme 14 Pro series will be launched at 12 noon on Thursday, January 16. Fans can catch the live-streamed event on Realme’s official YouTube channel.

Realme 14 Pro series specifications (Expected)

The Realme 14 Pro series, including the Realme 14 Pro and Realme 14 Pro+, has already been introduced in China, offering a sneak peek into its features.

The Realme 14 Pro boasts a 6.83-inch Full HD+ AMOLED display with a 120Hz refresh rate and an impressive 3840Hz PWM dimming for superior visuals. Under the hood, the smartphone is powered by the Snapdragon 7s Gen 3 processor, coupled with up to 12GB LPDDR4X RAM and 512GB UFS 3.1 storage. It is expected to run on Android 15 with Realme UI 6.0.

For photography, the device offers a triple-camera setup featuring a 50MP Sony IMX896 primary sensor with OIS, an 8MP ultra-wide lens, and a 50MP Sony IMX882 periscope telephoto lens with up to 6x in-sensor zoom. The front houses a 32MP selfie camera.

Additional features include an in-display fingerprint sensor, IP66, IP68, and IP69 water resistance certifications, and a robust 6,000mAh battery with 80W SuperVOOC fast charging.

Realme 14 Pro+ pricing (Expected)

The Realme 14 Pro+ is expected to be priced at approximately Rs 30,000 for the 12GB RAM/256GB storage variant and Rs 33,000 for the 12GB RAM/512GB version, based on its Chinese pricing of 2,599 yuan and 2,799 yuan, respectively.

As more details about the Realme 14 Pro surface, all eyes will be on tomorrow’s launch event for official specifications and pricing.

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