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Scientists studying a flatworm to explore possibility of skin tissue regeneration

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Scientists studying a flatworm to explore possibility of skin tissue regeneration

By Ratneshwar Thakur

Planaria are fresh water flatworms with an ability to regenerate from almost any number of pieces to form a completely new being

New Delhi: In an ideal world, one would like to live with no deformities. How often you think about being able to re-grow limbs after an amputation or any injury. Imagine being able to regenerate your spinal cord after an accident has left you paralyzed. Nature has many examples of some tiny organisms completely re-growing from their small pieces. Scientists are studying such organisms to learn important lessons in regeneration.

Researchers at the Bengaluru-based Institute for Stem Cell Biology and Regenerative Medicine have reported that deformities in the epidermis (outer skin layer) of an organism called planaria cause the defect in their stem cell function and regeneration. This is significant because epidermal cells are not stem cells.

Planaria are flatworms that live in fresh water and have the ability to regenerate from almost any pieces to form a completely new animal with all functional organ systems. Researchers used planaria as a model organism to understand the mechanism behind its immense regenerative ability.

“Our study has shown how the organization of epidermal cells during planarian regeneration is crucial for regulating stem cell function,” said Dr. Dasaradhi Palakodeti, a scientist at the Bengaluru based Institute, and a co-author of the study published in the journal Development.

Regeneration is often synonymous with stem cells and most of the studies focus on understanding factors essential for ‘stemness’. “Here, for the first time we show how planarian epidermis (non- stem cell) plays a critical role in wound healing and stem cell function,” said Dhiru Bansal, first author of this paper.

However, it is still unclear how the environment surrounding stem cells regulates their function. Researchers believe stem cells are instructed by surrounding cells to make right decisions to proliferate and differentiate for regeneration, to give rise missing tissues. The team is working to understand the role of a specific protein called PABPC2 (cytoplasmic poly A binding protein) in regeneration.

“Our report about a crosstalk between stem cells and epidermis in planaria opens new possibilities that can be addressed in other systems as well,” said Jahnavi Kulkarni, one of the authors of this paper.

The study opens up a new possibility to discover the role of non-stem cells in the skin regeneration. Skin is often well-thought-out for its protective function but this new study highlights other potential roles of the skin.

The research team included Dhiru Bansal, Jahnavi Kulkarni, Kavana Nadahalli, Vairavan Lakshmanan, Srikar Krishna, Vidyanand Sasidharan, Shilpa Dilipkumar, Akash Gulyani, Srikala Raghavan and Dasaradhi Palakodeti (Institute for Stem Cell Biology and Regenerative Medicine, Bangalore); Jini Geo and Renu Pasricha (National Centre for Biological Sciences, Bangalore).

(This article is from a syndicated feed provided by the India Science Wire)

Gadgets

Samsung Galaxy S25 FE India price leak suggests launch similar to S24 FE

Samsung Galaxy S25 FE India price has surfaced online, hinting at a similar launch price as the S24 FE. The phone brings a 6.7-inch AMOLED display, Exynos 2400 chip, triple rear cameras, and a 4,900mAh battery.

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Samsung Galaxy S25 FE, which was unveiled globally on September 4, is yet to receive official pricing for the Indian market. However, a fresh leak indicates that the handset could debut in India at the same price point as its predecessor, the Galaxy S24 FE.

Expected price and availability in India

According to tipster Yogesh Brar, the Samsung Galaxy S25 FE may be priced at ₹59,999 for the base 8GB RAM + 128GB storage variant in India. This matches the launch price of last year’s Galaxy S24 FE, which started at ₹59,999 for the same configuration. The higher 8GB RAM + 256GB model of the S24 FE was earlier priced at ₹65,999.

Globally, the Galaxy S25 FE has been introduced at $650 (around ₹58,000) for the base variant and $710 (around ₹63,000) for the 8GB + 256GB version. In India, the smartphone is expected to go on sale in October, similar to last year’s rollout schedule for the S24 FE.

The phone is offered in Icyblue, Jetblack, Navy, and White colour options.

Key specifications

  • Display: 6.7-inch full-HD+ Dynamic AMOLED 2X, 120Hz refresh rate, 1,900 nits peak brightness, Vision Booster, Gorilla Glass Victus+ protection.
  • Processor: Exynos 2400 SoC.
  • RAM & Storage: 8GB RAM standard, up to 512GB UFS 4.0 storage.
  • Rear Cameras: 50MP wide-angle + 8MP telephoto + 12MP ultrawide; 8K video recording at 30fps.
  • Front Camera: 12MP selfie shooter.
  • Battery: 4,900mAh with 45W wired and 15W wireless charging.
  • Build: 7.4mm thick, 190g weight, IP68-rated water and dust resistance.
  • Cooling: 10% larger vapour chamber compared to the Galaxy S24 FE.

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Gadgets

iPhone 17 series launched in India: Price starts at Rs 82,900, goes up to Rs 2.29 lakh

Apple has launched the iPhone 17 series in India with prices starting at Rs 82,900. Pre-booking begins on 12 September, and the phones will be available from 19 September.

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iphone 17

Apple has officially launched its much-awaited iPhone 17 series in India, introducing four models – iPhone 17, iPhone 17 Air, iPhone 17 Pro and iPhone 17 Pro Max. The series comes with advanced features, multiple storage variants, and a starting price of Rs 82,900. Pre-bookings will open from 12 September, while sales begin on 19 September.

iPhone 17 and iPhone 17 Air price in India

The standard iPhone 17 is priced at Rs 82,900 for the 256GB base variant. Meanwhile, the iPhone 17 Air, designed with a slimmer and more premium look, starts at Rs 1,19,900.

Key features of iPhone 17

  • Display: 6.3-inch Super Retina XDR OLED, 120Hz ProMotion, up to 3000 nits brightness with Ceramic Shield 2 protection.
  • Camera: Dual 48MP setup (Fusion main + Ultra Wide) with 2X telephoto capability, along with a new Centre Stage front camera.
  • Performance: Powered by the A19 chipset, runs on iOS 26, 40% faster than iPhone 16.
  • Battery: Up to 8 hours longer backup compared to its predecessor.

iPhone 17 Pro and Pro Max price in India

The premium segment begins with iPhone 17 Pro priced at Rs 1,34,900, while the iPhone 17 Pro Max starts at Rs 1,49,900. The top-end Pro Max with the highest storage option goes up to Rs 2,29,900. These models are available in Cosmic Orange, Deep Blue, and Silver colours.

Key features of Pro models

  • Display: iPhone 17 Pro with 6.3-inch and Pro Max with 6.9-inch Super Retina XDR OLED, both featuring 120Hz refresh rate and 3000 nits brightness.
  • Chipset: New A19 Pro with Vapour Chamber Cooling for heavy usage.
  • Camera: Triple 48MP system including an advanced telephoto lens with 8X optical zoom and 40X digital zoom, plus an 18MP front camera.
  • Battery & Charging: Best-ever battery backup on Pro Max, with USB-C fast charging – 50% charge in just 20 minutes.

Why the iPhone 17 series stands out

The new iPhones not only bring improved design and performance but also integrate Apple Intelligence AI features for messaging, calls and visual tools.

Offers and EMI options

  • No-cost EMI: Available for up to 6 months.
  • Cashback: ICICI Bank users can avail up to Rs 5,000 instant cashback.
  • For instance, buying the iPhone 17 Pro Max (Rs 1,49,900) on a 6-month no-cost EMI plan brings effective savings of Rs 11,525, including cashback and EMI benefits.

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Gadgets

Lava Yuva Smart 2 launched in India with 5,000mAh battery and dual cameras

Lava has launched the Yuva Smart 2 in India with a 5,000mAh battery, dual cameras, Android 15 Go Edition, and a price tag of Rs 6,099.

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Lava phone

Lava has introduced its latest entry-level smartphone, the Lava Yuva Smart 2, in India. Priced at Rs 6,099, the device offers a large display, a massive battery, and dual cameras, making it a budget-friendly choice for first-time smartphone buyers.

Lava Yuva Smart 2 price and availability

The Yuva Smart 2 is priced at Rs 6,099 for the single 3GB RAM + 64GB storage variant. It will be available in Crystal Blue and Crystal Gold colour options. Lava has announced doorstep service across India, though official sale dates are yet to be disclosed.

Lava Yuva Smart 2 specifications

The smartphone runs on Android 15 Go Edition and is powered by the Unisoc 9863a octa-core chipset. It comes with 3GB RAM (expandable up to 6GB with virtual RAM) and 64GB internal storage.

It features a 6.75-inch HD+ display with a 90Hz refresh rate. For photography, the phone sports a 13MP AI dual rear camera housed in a square module, along with a 5MP front camera for selfies.

Backed by a 5,000mAh battery with 10W wired charging via USB Type-C, the device also includes a side-mounted fingerprint scanner and face unlock support for security.

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