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BENTA: What is it? All you need to know about the disease that infected a 7-month-old in Bengaluru

Recently, a seven-month-old infant in Bengaluru, Vijayandra, has been diagnosed with BENTA disease. This disease is extremely rare and serious. Worldwide, only 14 children have been diagnosed with the disease, out of which, Vijayandra is the youngest.

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BENTA disease

Since Covid-19, the entire world in alive anxious breaths to live a healthy life. People are getting more affected by health issues and diseases, and this fear becomes more threatening when the news of deaths, as well as young lives getting affected reaches us. Recently, a seven-month-old infant in Bengaluru, Vijayandra, has been diagnosed with BENTA disease. This disease is extremely rare and serious. Worldwide, only 14 children have been diagnosed with the disease, out of which, Vijayandra is the youngest. Vijayadra’s case is the world’s first BENTA case to be detected at such an early stage in terms of age and severity.

According to the DKMS BMST Foundation India, the toddler’s life can only be saved by blood stem cell transplant. It has also been reported that the Bengaluru-based blood stem cell registry has been searching for a match for the child.

What is BENTA disease?

BENTA disease is a rare immune system genetic condition. BENTA is caused by germline heterozygous gain-of-function mutations in the gene that produce B cell growth with NF-B and T cell anergy CARD11. It is characterised by excessive amounts of particular immune cells, starting since childhood.

B-cells are a kind of immune cell found in the bone marrow, and their frequency is more than usual in this case. T-cells are immune cells that mature in the thymus, a delicate organ under the breastbone in the upper chest. NF-B is a protein complex that regulates gene expression, or how many genes are turned on or off. Anergy is an immunological response to foreign chemicals that is less-than-normal (T cell).

What are the symptoms of BENTA disease?

An enlarged spleen, swollen lymph nodes, immunodeficiency, and an increased risk of lymphoma, a kind of cancer, are all symptoms of BENTA illness.  

Spleen enlargement (splenomegalia) and recurrent ear, sinus, and lung infections are the most common symptoms early in life.

Who are more likely to be infected with BENTA disease?

An individual is born with two copies of the CARD11 gene, one from the mother, and the other from the father. Children of people with the CARD11 mutation have a 50% chance of inheriting the mutation. For a person to develop BENTA disease, just one of the two copies of CARD11 must be abnormal.

Treatment of BENTA disease

Currently, there is only a limited therapy option for BENTA disease. Infections and symptoms of monoclonal or oligoclonal B cell growth, which might suggest B cell malignancy, are constantly observed in patients. Splenectomy is unlikely to diminish B cell load as three patient’s peripheral blood B cell counts increased dramatically after the surgery. Immunosuppressive medications, such as B cell-depleting therapies like rituximab, have yet to be proven beneficial in the treatment of BENTA illness.

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Health

Is winter really a silent threat for diabetics and hypertensive patients? Risks you need to know

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A person with diabetes and hypertension taking precautions during winter.

As the winter chill sets in, many people find themselves reaching for extra layers or cozy blankets to stay warm. But for those living with diabetes and hypertension, the cold weather could pose more serious threats than you might realize. Recent findings reveal that individuals with these conditions could face an increased risk of severe complications, including stroke and heart attack, during the colder months. Is your health at risk this winter? Let’s dig deeper into the chilling reality.

Cold weather and its impact on hypertension and diabetes

When the temperature drops, the body undergoes various physiological changes to protect itself. For people with hypertension, or high blood pressure, the cold causes blood vessels to constrict, raising blood pressure and increasing the risk of heart attack and stroke. The colder weather also causes the body to release more stress hormones, which can further elevate blood pressure levels. But the danger doesn’t stop there for diabetics.

Diabetes patients already struggle with poor circulation, and the winter chill can exacerbate this, leading to higher blood sugar levels and increased chances of complications like nerve damage. Experts are also warning about the added stress on the heart, as diabetics are already at a higher risk of cardiovascular diseases.

Health professionals are urging individuals with hypertension and diabetes to take extra precautions during the winter months.

Real-Life incidents raising alarm

There have been multiple reports from hospitals across India indicating a rise in patients suffering from heart attacks and strokes during the colder months. In fact, many of these patients were already dealing with hypertension or diabetes.

A recent case in Bengaluru highlighted this growing concern. A 62-year-old man, who had been managing his high blood pressure for years, was rushed to the emergency room after he suffered a stroke just days after a cold front hit the city. Doctors confirmed that the drop in temperature likely played a key role in the incident.

Taking preventive measures

So, how can diabetics and hypertensive individuals protect themselves during the cold season? Experts recommend the following:

Regular Monitoring: Keep a close watch on your blood pressure and blood sugar levels. With temperature changes, your levels could fluctuate, so make sure you’re regularly checking them.

Stay Warm: Layer up to stay warm but avoid overexerting yourself in extreme cold.

Medication Management: Be cautious about skipping or altering your medication routine. Talk to your doctor about any adjustments needed for winter months.

Exercise Caution Outdoors: Avoid going out during extreme cold, and if you must, ensure you’re properly dressed and limit time spent outside.

Hydration and Diet: Staying hydrated and maintaining a balanced diet is key to managing both blood sugar and blood pressure levels, particularly in colder weather.

As temperatures dip across the country, it’s important for those with hypertension and diabetes to take extra precautions. While winter might seem like a time for cozy warmth, for individuals with these conditions, it could be a hidden danger. Understanding the risks and taking preventive measures can help safeguard your health, ensuring that winter remains a season of comfort rather than complications.

Stay safe, stay warm, and keep your health in check.

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Health

Can you believe these secret turmeric remedies for cavities will transform your dental health?

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Turmeric and coconut oil mix for tooth decay treatment

Dental care is often overlooked, but even the slightest neglect can lead to significant problems. One of the most common issues is cavities, which are not only painful but can also be expensive and time-consuming to treat. While dental procedures can be costly, there is a natural and effective solution available in Ayurveda: turmeric. Known for its powerful antibacterial and antiseptic properties, turmeric has long been used in traditional medicine for various health benefits, including oral health.

The magical effects of turmeric

Turmeric contains a compound called curcumin, which is renowned for its ability to reduce inflammation and fight infections. Acting as a natural antibiotic, it helps eliminate bacterial infections in the teeth, making it a potent remedy for cavities. Regular use of turmeric can help reduce the damage caused by cavities and prevent further dental issues.

How to use turmeric and oil for cavity treatment?

One of the most effective ways to combat tooth decay is by combining turmeric with coconut oil. Here’s how you can use this powerful duo for healthier teeth.

Ingredients needed:

  • 1 teaspoon turmeric powder
  • ½ teaspoon coconut oil
  • A pinch of salt (optional)

Instructions:

  1. Mix the turmeric powder and coconut oil in a bowl until you get a smooth paste.
  2. Add a pinch of salt, if desired.
  3. Apply this mixture directly to the affected tooth and leave it for 10-15 minutes.
  4. Rinse your mouth with warm water after the treatment.
  5. Repeat this process twice daily for the best results.

Other natural remedies for cavities

Besides turmeric, there are a few other home remedies that can help treat cavities and promote overall dental health:

  • Clove Oil: Clove oil is highly effective in relieving tooth pain and preventing infections. It can be applied directly to the affected area using cotton wool.
  • Salt and Mustard Oil: A mixture of salt and mustard oil can be used to massage the gums. This not only helps in eliminating cavities but also strengthens the gums.
  • Neem Leaves: Chewing neem leaves or gargling with neem leaf extract can eliminate bacteria and promote healthy teeth and gums.

Additional benefits of turmeric

Turmeric is not only beneficial for fighting cavities but also offers several other advantages for oral health:

  • Teeth Whitening: Turmeric can help whiten and brighten your teeth when used regularly.
  • Reducing Gum Inflammation: It has anti-inflammatory properties that can reduce swelling and inflammation in the gums.
  • Fresher Breath: Turmeric’s antiseptic qualities can help eliminate bad breath and promote fresher-smelling breath.

Precautions

While turmeric is beneficial, it should not be left on the teeth for prolonged periods as it may cause yellow stains.
If your dental issue is severe, it’s always a good idea to consult with a dentist before relying solely on home remedies.

Using turmeric and coconut oil as a natural solution for cavities is not only affordable but also incredibly effective. With regular use, you can maintain healthy teeth and avoid costly dental procedures. Make turmeric a part of your daily routine for a brighter smile and healthier teeth.

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Health

India registers 313 new Covid cases, active cases reach 2,041, 3 deaths recorded in last 24 hours

The currently available data suggests that the JN.1 variant is neither leading to an exponential rise in the new cases nor a rise in the hospitalization and mortality.

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India saw a single-day rise of 313 new Covid cases, while the active caseload has declined to 2,041, the health ministry said on Saturday.  Three deaths: two from Karnataka and one from Maharashtra were reported in the last 24 hours.

According to the ministry website, the number of active cases in the country stood at 2,331 on Friday. The number of cases of Covid had dropped to double digits till December 5, but it began to start increasing after the emergence of a new variant and cold weather conditions.

 According to reports after December 5, the highest single day rise of 841new cases was reported on December 31, 2023, which is 0.2% of the peak cases reported in May 2021. Of the total active cases, a large majority of these (around 92%) are recovering under home isolation.

The currently available data suggests that the JN.1 variant is neither leading to an exponential rise in the new cases nor a rise in the hospitalization and mortality. India has witnessed three waves of Covid in the past with its peak incidence of daily new cases and deaths being reported during the delta wave in April June 2021.

 At its peak, 414,188 new cases and 3915 deaths were reported on May 7, 2021. Since the pandemic started in early 2020, there have have been 4.5 crore people who have got infected and this has resulted in the death of 5.3 lakh persons in a total time span of four years.

According to the ministry data, the total number of persons who have recuperated from the disease are 4.4 crore with total recovery rate recorded is 98.81%. A total number of 220.67 crore doses of Covid vaccines have been administered in India so far.  

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