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President Droupadi Murmu launches India’s first homegrown CAR T-cell therapy for cancer treatment

The gene-based therapy, which is developed by the IIT Bombay and Tata Memorial Centre, is being rolled out in India at about one-tenth of its price outside the country.

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President Droupadi Murmu on Thursday launched India’s first indigenously-developed CAR T-cell therapy, a gene-based therapy, for cancer treatment, hailing it as a breakthrough that provides new hope for humankind in the battle against the diseases.

Speaking at the launch event at the Indian Institute of Technology (IIT) Bombay, Murmu said the indigenous development of the CAR T-cell therapy was an example of the Make in India initiative.  

The gene-based therapy, which is developed by the IIT Bombay and Tata Memorial Centre, is being rolled out in India at about one-tenth of its price outside the country, as per the senior official.

In CAR T-cell therapy, a patient’s T-cells, which is a type of immune system cell or stem cell, are modified in the laboratory and inserted back into the patient to attack and destroy cancer cells after editing the stem cell.

The NexCAR19 CAR T-cell therapy, the country’s first Made in India CAR T-cell therapy, is expected to bring down the cost of treatment significantly.

During her speech, Murmu said that this therapy is considered a phenomenal advance in medical sciences. The development of this therapy is also an example of the Make in India initiative and speaks volumes about Indian scientists and physicians, she added.

The launch of India’s first gene therapy is a significant breakthrough in the battle against cancer. As this line of treatment, named CAR T-cell therapy, is accessible and affordable, it provides a new hope for the whole of humankind, President Murmu further added.

The Tata Memorial Centre director Sudeep Gupta said the CAR T-cell therapy was enormously expensive and out of the reach of an overwhelming majority of people.

Asserting that, he said NexCar19 needs to be custom manufactured for every patient under the most stringent conditions, but it has been rolled out at approximately one-tenth of the price at which it is available outside India.

The treatment costs approximately Rs 4 crore abroad against Rs 30 lakh in India, said IIT Bombay director Prof Subhasis Chaudhuri.

He further said that the low-cost CAR T-cell therapy was a huge achievement for the country and cancer patients, and places India firmly on the global map of cell and gene therapy.

Comparing the achievement of Chandrayaan-3 with CAR T-cell therapy, Chaudhuri asserted that CAR-T cell therapy heralds India’s entry into the cell and genetic engineering group.

The Tata Memorial Centre director Gupta said the treatment will help some 20,000 Indians every year, and its rollout is a milestone in the field of cancer care and genetic engineering.

He added the CAR T-cell was not only a scientific achievement of the highest order but also had immense practical application. NexCAR19 will save many, many lives and wipe many, many tears, he emphasised.

India News

Sunita Kejriwal, Atishi meet Arvind Kejriwal in Tihar jail, discuss Delhi governance

AAP had earlier accused the Tihar jail administration of cancelling Sunita Kejriwal’s meeting with Arvind Kejriwal.

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Delhi Chief Minister’s wife Sunita Kejriwal and AAP minister Atishi met Arvind Kejriwal in the Tihar Jail today. After their meeting, both dicussed the specifics of their meeting with CM. They said that the jailed CM was asking about the Delhi governance matter.

Kejriwal is expected to see Punjab Chief Minister Bhagwan Mann tomorrow.

Atishi, who is in charge of six departments in the Delhi Cabinet, said, she visited with the Chief Minister. When she asked how he was doing, he skipped answering her, rather he asked how the work is going in Delhi. He said, not to ask about his condition. During their meet, the Delhhi CM also asked about the school kids that are they getting books? Does Mohalla Clinic have access to medications? Atishi continued.

The Chief Minister said that as summer is approaching, Delhi shouldn’t have any water-related issues. He sent a message to the women of Delhi, saying he is planning to give them Rs 1000.

The Aam Aadmi Party had earlier claimed that Kejriwal’s wife, Sunita Kejriwal, was not allowed to see him. However, in a statement, Delhi minister Atishi said that Sunita Kejriwal will see her husband later on in the day and that two people were granted permission, but Sunita ji’s was cancelled. Athishi said, every day, new laws are enacted, she did not have permission, but when their lawyers won this legal battle, she was permitted to see Kejriwal.

AAP’s campaign for the Lok Sabha in the national capital and other states will be led by Mrs. Kejriwal, the party said. The campaign kicked off with a roadshow to support AAP’s candidate for East Delhi, Kuldeep Kumar. This is the first time that Mrs. Kejriwal has entered the political sphere actively.

Party leader Sanjay Singh asserted last week that Atishi’s name was added to the list of visitors for Mr. Kejriwal following the name of Delhi Health Minister Saurabh Bharadwaj.

Meanwhile, in the Delhi Liquor Policy case, Arvind Kejriwal was taken into custody in March. On March 21, the Enforcement Directorate (ED) detained him in connection with a money laundering case. In the same case, Manish Sisodia, his former deputy, is jailed.

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FIR filed against YouTube channel in Punjab for defaming AAP MP Raghav Chadha

The case was filed on the complaint of the son of an AAP candidate from the Ludhiana Lok Sabha seat.

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A First Information Report (FIR) has been filed by Punjab Police against a YouTube channel for allegedly linking Aam Aadmi Party (AAP) MP Raghav Chadha to wanted man Vijay Mallya.

The AAP candidate for the Ludhiana Lok Sabha constituency, Ashok Pappi Prashar’s son, Vikas Prashar, filed a formal complaint against the YouTube station Capital TV. The complainant held the channel accountable for airing misleading and defamatory content.

The statements/contents of false videos on Capital TV channel and others shall harm the public peace and harmony…and is likely to promote enmity between different groups in the country on grounds of religion, caste, race and community, the complaint said.

In his complaint, Vikas allegedly claimed that the YouTube channel was disseminating misleading information and that it was defaming Raghav Chadha by equating him with Mallya.

Vijay Mallya fled to the UK after taking public money, and similarly, a Rajya Sabha member left for England, claiming it was for eye treatment, according to the FIR, which noted claims made by the YouTube channel.

The AAP leader will reportedly get a vitrectomy in the UK to save the retina from detaching from the eye earlier. According to the research, this disorder, which is characterized by the formation of tiny holes in the retina, is very dangerous for vision and must be treated immediately to prevent irreversible damage.

The channel referred to Chadha as a Khalistani supporter following his encounter with UK MP Preet Gill, according to the complaint.

Section 153A of the Indian Penal Code (IPC) deals with inciting religious hatred among various groups, Section 469 deals with forgeries, and Section 505 deals with making statements that could incite public disturbances.

The FIR also contains Section 66 of the Information Technology Act, which addresses offenses involving computers.

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Security forces arrest 14 Pakistani nationals with around 86 kg of drugs, worth Rs 600 crore near Gujarat Coast

The Indian Coast Guard took to X and wrote in a breathtaking overnight operation, Indian Coast Guard undertook an intelligence-based anti-narcotics operation at sea on 28 Apr 24. About 86 kg of narcotics which is worth Rs 600 crore has been apprehended along with the arrest of 14 Pakistani nationals.

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The Indian Coast Guard on Sunday announced the interception of a Pakistani vessel laden with 86 kg of narcotics valued at Rs 600 crore. Acting on intelligence, a joint operation involving the Indian Coast Guard, the Anti-terrorism Squad (ATS), and the Narcotics Control Bureau (NCB) was launched to combat drug trafficking in the area.

The operation was carried out by the agencies based on intelligence inputs received in the last few days. The Indian Coast Guard took to X and wrote in a breathtaking overnight operation, Indian Coast Guard undertook an intelligence-based anti-narcotics operation at sea on 28 Apr 24.

About 86 kg of narcotics which is worth Rs 600 crore has been apprehended along with the arrest of 14 Pakistani nationals. The operation was an epitome of inter-agency coordination wherein the Indian Coast Guard Anti-terrorism Squad and Narcotics Control Bureau  collaborated seamlessly which resulted in the successful operation.

The ships and aircraft of the Indian Coast Guard had been deployed on concurrent missions to carry out the operation. ICG ship Rajratan, which had Narcitics Control Bureau and Anti Terrorist Squad officials embarked, positively identified the suspect boat.

No amount of evasive maneuvering tactics and resistance employed by the drug laden Pakistani boat could save it from the swift and strong action of ICG ship Rajratan. This operation took place on the basis of a tip-off by the Indian Coast Guard, Narcotics Control Bureau and Gujarat Anti-Terrorist Squad in the Arabian Sea near the International Maritime Boundary Line.

The operation was the 2nd major anti-narcotics operation carried out by the security forces in the Arabian Sea in 1 month. Earlier on February 26, 5 foreign nationals were held off the Porbandar coast with 3,300 kg of narcotics, including charas. Recently a boat carrying 60 packets of drugs was seized and 6 Pakistani crew members onboard the vessel were arrested off the Gujarat coast in a multi-agency operation in March.

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