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Hope brightens for corona vaccine.

Oxford University has initiated a phase-1 human clinical trial of its vaccine against the novel coronavirus, SARS-CoV-2. A single dose of the candidate vaccine will be administered to 1,112 healthy volunteers to study the safety, ability to produce immune response and efficacy of the vaccine.

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Oxford University has initiated a phase-1 human clinical trial of its vaccine against the novel coronavirus, SARS-CoV-2. A single dose of the candidate vaccine will be administered to 1,112 healthy volunteers to study the safety, ability to produce immune response and efficacy of the vaccine. Oxford University is optimistic of a positive outcome of the candidate vaccine and has planned to get millions of doses of the vaccine before the end of the year even as results of the final phase of the trial are awaited.

The proposed vaccine for corona virus by Oxford University uses the common cold virus, adenovirus, that causes infections in chimpanzees. The adenovirus has been genetically altered so that it does not grow once injected. The construct carries the genetic material of the novel coronavirus that makes the spike protein. The spike protein is found on the surface of the virus and plays a crucial role in binding to specific human receptors found on cell surfaces and entering the cells.

By introducing the genetic material of the spike protein, the candidate vaccine will help the body recognise it and make antibodies against the spike protein. The antibodies produced will help mount an immune response and prevent the virus from entering the human cells and causing an infection.

Oxford University has used vaccines made from the adenovirus construct to over 320 people and has found it to be safe and well tolerated. It does cause transient side effects such as fever, headache or a sore arm but is otherwise safe.

The safety of the candidate vaccine was earlier tested on six rhesus macaque monkeys. A single dose protected all the six animals for nearly a month even when exposed to high levels of the virus, boosting the confidence of the researchers.

Up to 1,112 healthy volunteers have been recruited for the phase-1 trial. Volunteers, both male and female between 18-55 years, are being recruited for the trial. A single dose of the candidate vaccine will be administered to volunteers.  The university researchers will also be testing two doses of the candidate vaccine given four weeks apart on a small group of 10 volunteers to assess the dosage and immune response.

The phase-1 trial is expected to be completed by May-end if transmission remains high in the community. The phase-2 trial may be completed by August-September. In fact, phase-2 and phase-3 trials may get combined if the phase-1 trial results are encouraging.

Pune’s Serum Institute, a partner in the project, has said that the company will start manufacturing the vaccine the moment the phase-3 trial or the combined phase-2/phase-3 trial begins. If the last two stages of the trial are combined then it would start manufacturing the vaccine by June-end and be ready with millions of doses by the end of the year. The company is confident of manufacturing 60-70 million vaccine doses by the end of the year.

India News

Meta to face Indian parliamentary panel over Zuckerberg’s election remarks

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Mark Zuckerberg

Social media giant Meta will soon be summoned by India’s Parliamentary Standing Committee on Communication and Information Technology over CEO Mark Zuckerberg’s comments regarding the 2024 Indian general election. Nishikant Dubey, BJP MP and chairman of the panel, stated that Meta would be held accountable for allegedly spreading misinformation.

“Misinformation in a democratic country damages its image. The organization must apologize to the Parliament and the people for this mistake,” Dubey said in a post on X.

Zuckerberg, during a January 10 podcast, referred to the global erosion of trust in governments post-Covid. He claimed that in 2024, major elections worldwide, including India’s, saw incumbents losing power, linking this trend to factors such as inflation, economic policies, and pandemic handling.

The statement was swiftly fact-checked by Union Minister Ashwini Vaishnaw, who clarified that India’s 2024 general elections reaffirmed public trust in the NDA led by Prime Minister Narendra Modi.

“As the world’s largest democracy, India conducted its 2024 elections with over 640 million voters. People reaffirmed their trust in the NDA under PM Modi’s leadership. Zuckerberg’s claim is factually incorrect,” Vaishnaw posted on X.

He also highlighted Modi’s governance during Covid, emphasizing free food for 800 million citizens, 2.2 billion free vaccines, and economic recovery efforts that positioned India as a fast-growing economy. Vaishnaw expressed disappointment in Meta for allowing such misinformation, urging the platform to prioritize factual reporting.

While the BJP saw a slight dip in seats during the 2024 elections, the NDA comfortably retained power with its allies’ support. This marked Modi’s historic third consecutive term as Prime Minister, making him only the second Indian leader after Jawaharlal Nehru to achieve this milestone.

The controversy surrounding Zuckerberg’s remarks underscores the growing scrutiny of social media platforms in influencing political discourse and the need for accountability in the digital space.

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India News

Army vehicle accident in J&K claims two soldiers’ lives, two others injured

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Two soldiers were tragically killed and two others injured when an Army vehicle skidded off the road and plunged into a gorge in Jammu and Kashmir’s Bandipora district on Saturday.

The accident took place near the SK Payen area, leaving the soldiers with serious injuries. The injured personnel were promptly rushed to a nearby hospital for treatment, while the loss of the two soldiers has left the entire region in mourning.

This unfortunate incident follows another similar tragedy that occurred just a month ago in Poonch. In that accident, five soldiers lost their lives, and five others were injured when their truck fell into a 300-foot gorge. The Army’s White Knight Corps paid tribute to the fallen soldiers, sharing a statement on social media expressing their deepest condolences for the “brave soldiers” who had been serving on operational duty in the Poonch sector.

The latest loss has drawn widespread expressions of grief from political leaders. Jammu and Kashmir Chief Minister Omar Abdullah expressed his sorrow, while Congress leader Rahul Gandhi offered his heartfelt tributes to the martyrs. He also wished for a swift recovery for the injured soldiers and extended his deepest condolences to their grieving families.

These two incidents highlight the ongoing risks faced by soldiers in the line of duty, and the sacrifices made in protecting the nation. Authorities are continuing their investigation into the cause of the accident, while the military community comes together to mourn the tragic losses.

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India News

Aligarh man’s journey ends in arrest as Pakistani woman declines marriage proposal

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India-Pakistan International Border

A 30-year-old Indian man, Badal Babu, from Uttar Pradesh’s Aligarh district, is in judicial custody in Pakistan after illegally crossing the border to meet his Facebook friend, only to be rejected. The woman, identified as 21-year-old Sana Rani, told authorities she has no interest in marrying him.

The arrest took place in Mandi Bahauddin, a district in Pakistan’s Punjab province, roughly 240 kilometers from Lahore. Babu was detained under sections 13 and 14 of Pakistan’s Foreign Act for entering the country without proper documentation.

A Facebook friendship turns sour

According to Punjab police officer Nasir Shah, the duo had been friends on Facebook for over two and a half years. Babu, in love with Rani, decided to cross the border illegally to propose. However, Rani’s statement to the police made it clear she had no intention of marrying him.

Shah added, “Babu crossed into Pakistan illegally and reached Maung village, where he was apprehended. Whether he met Rani in person remains unclear.”

Family under scrutiny

Reports suggest that intelligence officials questioned Rani and her family about her relationship with Babu. Although there is speculation that Rani may have given her statement under duress, this remains unconfirmed.

Legal proceedings begin

Babu, who narrated his “love story” to authorities, was presented in court, which placed him in judicial custody for 14 days. His next hearing is scheduled for January 10.

A familiar tale across borders

Babu’s story echoes previous cross-border romances fostered through social media or online games.

  • In a widely publicized case, Indian woman Anju traveled to Pakistan to marry Nasrullah, converting to Islam before tying the knot.
  • Similarly, Seema Haider, a Pakistani woman, crossed into India via Nepal to marry her PUBG friend after bringing her four children along.
  • Last year, 19-year-old Pakistani girl Iqra Jiwani married Indian national Mulayam Singh Yadav in Nepal after meeting him online.

While these cases highlight the unifying power of social media, they also underscore the legal and personal challenges of navigating cross-border relationships.

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