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AI-Integrated retinal-imaging device from India shows promising results in screening for Diabetic Retinopathy

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AI-Integrated retinal-imaging device from India shows promising results in screening for Diabetic Retinopathy

ANI | Updated: Sep 12, 2019 14:02 IST

Bengaluru (Karnataka) [India] Sept 12(ANI/BusinessWire India): Diabetic Retinopathy (DR), is asymptomatic and affects nearly 20per cent of the 70 million diabetic patients in India.

Timely and accessible DR screening can enable early detection, preventing needless blindness. Nearly 70per cent of the population, especially those in rural areas lack access to specialists, given the very low specialist to population ratio of 1:100000 in some areas. A landmark study published in the August issue of JAMA Ophthalmology (Journal of the American Medical Association), reports the feasibility of using a smartphone-based retinal camera with the world’s first, in-built automated, offline Artificial Intelligence (AI) algorithm, the MEDIOS-AI, designed by Bangalore-based Remidio Innovative Solutions, to implement sensitive and scalable screening models for DR.

A team from Aditya Jyot Foundation for Twinkling Little Eyes, Mumbai, led by Dr Natarajan, President of the All India Ophthalmology Society, has till date screened more than 1300 patients with diabetes mellitus in civic dispensaries in Mumbai for DR and validated the diagnostic accuracy of MEDIOS-AI to detect Referable DR, a condition requiring immediate specialist consult. The AI instantly provides a report in less than 10 seconds, on the smartphone.

Florian Savoy (VP, Data Sciences and AI) and Bhargav Sosale (VP, Software Design), the architects of Remidio’s smartphone-based AI solution, suggest that the novel, offline AI platform is ‘extendable to Glaucoma, AMD and other sight-threatening chronic diseases’.

The images were captured on Remidio’s smartphone-based, non-mydriatic, portable camera, the NM-FOP 10 and subjected to automated analysis by MEDIOS-AI, with simultaneous grading by vitreoretinal specialists. MEDIOS-AI relied on 2 convolutional neural networks, based on the MobileNet architecture – one assessing the image quality, and the other separating healthy images from images with referable DR (RDR). The clinical sensitivity and specificity of the MEDIOS-AI algorithm were found to be 100per cent and 88.4per cent for RDR, 85.2per cent and 92.0per cent for any DR respectively, exceeding US FDA’s superiority endpoints of an RDR sensitivity of 85per cent and specificity of 82.5per cent.

Dr TY Alvin Liu, MD, Assistant Professor of Ophthalmology at Johns Hopkins Bloomberg School of Public Health, in an invited commentary, calls the study ‘paradigm-shifting’.

“The study paves the way in implementing large scale models for screening for DR, even in locations with no internet infrastructure. This is a step ahead of the approach taken by Google and other AI companies that need their AI models to run on external servers, necessitating internet access,” said Dr Natarajan, MD.

“Technologies like Remidio NMFOP and Medios Offline AI, are necessary to move screening closer to the nearly 400 million patients at risk of blindness globally, due to chronic, asymptomatic conditions like Diabetic Retinopathy,” said Dr Anand Sivaraman, CEO, Remidio.

This story is provided by Businesswire India. ANI will not be responsible in any way for the content of this article. (ANI/BusinessWire India)

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Partial solar eclipse 2025 today: Timings, livestreams, double sunrise effect and safety tips

The first solar eclipse of 2025, occurring today, will not be visible from India but can be watched online via livestreams by NASA and other observatories.

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Partial solar eclipse forming crescent Sun in sky

A partial solar eclipse, the first of the year 2025, is set to unfold today, March 29. While this celestial phenomenon will be observable from several parts of the world, it will not be visible from any region in India. The eclipse is expected to start around 2:20:43 PM IST and continue until 6:13:45 PM IST, with visibility dependent on geographic location.

What is a partial solar eclipse?

Unlike a total eclipse where the Moon entirely blocks the Sun, a partial solar eclipse leaves part of the Sun exposed. As the Moon partially covers the Sun, it creates a striking crescent-like shape in the sky. Today’s eclipse is also expected to produce a rare “double sunrise” effect — where the Sun appears to rise, dim briefly, and rise again — typically visible in areas where the eclipse coincides with sunrise.

A global event, but not for Indian skies

According to space data agencies, about 100 crore (1 billion) people will be in locations where they can witness this partial eclipse. However, only around 44,800 people will see at least 90% coverage of the Sun — marking a very limited population for the highest visibility range.

Watch safely — never directly

Experts strongly advise against looking at the Sun directly during any solar eclipse. Viewers should only use certified solar viewing glasses, eclipse glasses, or handheld solar viewers. Watching through regular cameras, binoculars, or telescopes without proper solar filters can lead to severe eye damage.

Livestreaming options for virtual viewing

For those in India and elsewhere who cannot witness the eclipse directly, several global platforms like NASA and SLOOH Observatory are offering live streaming on their websites and social media channels. Indian space authorities like ISRO may also stream the event live. Viewers can access real-time visuals and expert commentary from the comfort of their homes.

The eclipse pairing rule

Astronomers remind us that eclipses always occur in pairs. This solar eclipse follows a total lunar eclipse that occurred just two weeks ago. Another pair of solar and lunar eclipses is expected to occur in September 2025, in line with the seasonal pattern of eclipses occurring roughly six months apart.

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US President Trump says he will pay out of his pocket to Sunita Williams, Butch Wilmore for overtime stay in space

“Nobody told me about this. If it comes to it, I’ll pay it from my own pocket, alright? I’ll sort it for them,” Trump declared, visibly taken aback. “Is that it? That’s peanuts for what they’ve been through,” he added, marvelling at the modest sum given their ordeal.

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US President Donald Trump has expressed surprise upon learning that NASA astronauts Sunita Williams and Butch Wilmore, who endured an extended nine-month stint aboard the International Space Station (ISS), hadn’t received overtime pay.

Addressing reporters at a White House briefing, Trump even floated the idea of covering the costs himself, after the reporter highlighted that the duo were owed $1,430—$5 daily for 286 days.

“Nobody told me about this. If it comes to it, I’ll pay it from my own pocket, alright? I’ll sort it for them,” Trump declared, visibly taken aback. “Is that it? That’s peanuts for what they’ve been through,” he added, marvelling at the modest sum given their ordeal.

The astronauts, including Williams and Wilmore, alongside Nick Hague and Russian cosmonaut Aleksandr Gorbunov, returned to Earth on Wednesday via SpaceX’s Dragon spacecraft, splashing down off Tallahassee, Florida.

Trump showered praise on SpaceX chief Elon Musk for the rescue. “Thank heavens for Elon. Without him, who knows how long they’d have been stuck up there?” he remarked, crediting Musk’s ingenuity for their safe return.

For Williams and Wilmore, seasoned test pilots for Boeing’s Starliner capsule, what began as an eight-day mission ballooned into over nine months due to technical snags—helium leaks and thruster glitches—that rendered their craft unfit for the journey back.

The Starliner returned empty in September 2024, leaving them reliant on SpaceX. Trump underscored the physical toll of prolonged space stays. “After nine or ten months, the body starts breaking down—bones, blood, the works. It gets grim beyond 14 months. Without Elon, they’d be in a fix,” he said.

In a tangent, Trump drew parallels between Musk’s challenges and his own, claiming Tesla faced vandalism akin to the 6 January 2021 riots. “Elon’s had his share of trouble too,” he noted, blending admiration with a touch of defiance.

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Sunita Williams returns home after 286 days at space, greeted with smiles and applause

Astronaut Sunita Williams returned home after an unplanned 286-day mission in space, originally intended to last only eight days.

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Sunita Williams waving after returning from space

NASA astronaut Sunita Williams and her crewmate Butch Wilmore have successfully returned to Earth after spending an unexpected 286 days in space. Originally meant to be an eight-day mission, the duo faced prolonged delays due to technical issues with the Boeing Starliner spacecraft, which left them stranded aboard the International Space Station (ISS).

Williams and Wilmore finally made their journey back aboard SpaceX’s Dragon spacecraft, which splashed down in the ocean near Florida. The mission, which initially launched on June 5 last year, concluded with a safe landing early this morning.

Splashdown near Florida

After spending 17 hours in transit back to Earth, the capsule deployed its parachute, ensuring a controlled descent before making a water landing. NASA teams were on standby to retrieve the astronauts, assisting them onto mobility aids as they adapted to Earth’s gravity.

Williams was seen waving and flashing thumbs-up signs as she emerged from the capsule, signaling a positive return despite the physical challenges posed by prolonged space travel.

SpaceX ensures safe return

The return of the astronauts was made possible through SpaceX’s Crew-9 mission. The Dragon capsule, which was launched atop a Falcon 9 rocket, was sent to replace Crew-9 at the ISS. The spacecraft undocked at 10:35 am (IST), with NASA sharing visuals of the departure.

From an eight-day mission to nine months in space

Williams and Wilmore initially traveled to the ISS on what was to be the first crewed flight of Boeing’s Starliner spacecraft. However, the Starliner developed propulsion issues and was deemed unfit for the return journey. NASA reassigned them to SpaceX’s Crew-9, and in September, a Dragon capsule was sent with a two-member crew to ensure their safe return.

After multiple delays, a relief team finally arrived on Sunday, paving the way for their journey home.

Challenges faced by returning astronauts

A prolonged stay in space presents multiple health challenges. Astronauts experience muscle and bone density loss due to the lack of gravity, which can lead to long-term physical impairments. NASA estimates that for every month in space, astronauts’ weight-bearing bones lose approximately one percent of their density.

Radiation exposure is another concern, as the Earth’s atmosphere provides protection that is unavailable in space. Vision impairment and weakened muscles are also common issues faced by astronauts after extended space travel.

PM Modi acknowledges Sunita Williams’ achievements

Ahead of her return, Indian Prime Minister Narendra Modi sent a letter to Sunita Williams, praising her resilience and contribution to space exploration. The letter, dated March 1 and shared publicly by Union Minister Jitendra Singh, expressed India’s pride in Williams’ achievements.

PM Modi mentioned that he had discussed Williams’ mission with both former US President Donald Trump and his predecessor, Joe Biden, during his visits to the United States. “1.4 billion Indians have always taken great pride in your achievements. Recent developments have yet again showcased your inspirational fortitude and perseverance,” the letter read.

Williams’ return marks the end of an eventful mission filled with challenges and triumphs, further reinforcing her legacy as a seasoned space traveler.

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