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Cultural factors too influence intestinal health

[vc_row][vc_column][vc_column_text]By Monika Kundu Srivastava
New Delhi, June 14 (India Science Wire): Intestinal health is known to be influenced by environmental, biological and genetic factors. A new study suggests that ethnicity – a cultural factor – may also have a role to play in keeping our stomachs healthy.
Gut microbes, especially bacteria, are essential to maintain good digestive health. Therefore, a study of bacteria and metabolites could yield important clues to any person’s health. Scientists at the Institute of Advanced Study in Science and Technology, Guwahati, have attempted to do this among members of tribal communities. They have found that the type of gut bacteria found among people vary with their ethnicity.
The study included 39 men and women belonging to five tribes – Tea-tribe (which has a Proto-Australoid origin), Bodo, Karbi, Tai-Phake and Tai-Aiton tribes of Mongoloid origin. All study participants were of rural background, practiced farming and were non vegetarian. Rice is their staple food along with cereals, vegetables and tubers. The study builds on earlier work done at the institute, which had shown a similarity in gut microbe profiles of the Tea-tribe and Tai-Phake and between Tai-Aiton, Bodo and Karbi tribes.
Individuals of same ethnic group had more similar profiles of gut bacteria and their metabolites. This has important implications for health. For instance, the metabolite profile of the Tea-tribe contained aniline, benzoate and acetaldehyde which may cause colorectal cancer. “This finding is significant as people from the community can be made aware of the risk they face and suitable preventive measures can be initiated such as regular follow-ups for any signs of the disease,” explained Dr. Mojibur R Khan, who led the study. Additionally, useful Lactobacillus and Roseburia bacteria or butyric acid supplements can be given to people to prevent colorectal cancer.
Regular analysis of metabolites could be cheaper way to keep track of persons who are at risk of acquiring a disease. On the other hand, more expensive tests to detect presence of cancer cells can be done only when there is a clear indication of disease.
The study offers hope to ethnic groups in India and around the world by encouraging researchers to identify population-specific disease markers through gut and metabolite profiling useful for prevention, early detection and intervention of disease. Subsequently, cheap diagnostic tests can be developed using the profiling data.
The team of researchers included Madhusmita Dehingia, Supriyo Sen, Bhuwan Bhaskar, Tulsi K. Joishy, Manab Deka, Narayan C. Talukdar. The study results have appeared in scientific journal Metabolomics. (India Science Wire)[/vc_column_text][/vc_column][/vc_row]

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Chandrayaan-3: ISRO postpones plans to reactivate Vikram Lander, Pragyan Rover on September 23
After Chandrayaan-3’s Vikram Lander and Pragyan Rover soft landing on the South Pole of the Moon on August 24, both Vikram and Pragyan functioned effectively for a duration of 14 Earth days. The Rover was put on sleep mode on September 2, while the Lander was on September 4.

The Indian Space Research Organisation on Friday postponed the plans to reactivate Vikram Lander and Pragyan Rover to September 23.
After Chandrayaan-3’s Vikram Lander and Pragyan Rover soft landing on the South Pole of the Moon on August 24, both Vikram and Pragyan functioned effectively for a duration of 14 Earth days. The Rover was put on sleep mode on September 2, while the Lander was on September 4.
They were put on sleep mode for approximately 16 Earth days before the lunar night enveloped the south pole of the Moon.
Speaking on Chandrayaan-3’s Vikram Lander and Pragyan Rover, Nilesh Desai, Director of Space Application Centre said that earlier we planned to reactivate the Pragyan Rover and Vikram Lander on the evening of September 22, but due to some reasons we will do it on September 23, said Desai.
He further said a plan to take out the Lander and Rover from the sleep mode and reactivate it, adding that, we had a plan to move the Rover to almost 300 to 350 metres but due to some reasons, the Rover has moved 105 metres there.
In collaboration with MyGov, ISRO has invited the citizens to participate in the Chandrayaan-3 Mahaquiz. The step was taken with the motive to honour India’s amazing space exploration journey. This will help to explore the wonders of the moon and show our love and passion for science.
In order to participate in the Chandrayaan-3 Mahaquiz, the participants would be required to create an account on the MyGov website. There is a cash prize for the winners and it also allows individuals to download the certificate.
Earlier, the Laser-Induced Breakdown Spectroscope (LIBS) instrument onboard the Pragyan rover also detected aluminium, calcium, iron, chromium, titanium, manganese, silicon and oxygen, as expected.
ISRO also shared a graph of the observation on X, illustrating the temperature variation of the lunar surface at various depths, as recorded during the probe’s penetration.
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Aditya L1 successfully undergoes 4th earth-bound manoeuvre: ISRO
The Indian Space Research Organisation said that the Aditya L1 spacecraft successfully underwent the fourth earth-bound manoeuvre on Friday.

The Indian Space Research Organisation said that the Aditya L1 spacecraft successfully underwent the fourth earth-bound manoeuvre on Friday. This is India’s first space-based mission to study the Sun.
ISRO took to X, formerly Twitter and informed that the fourth earth-bound manoeuvre (EBN4) was performed successfully. ISRO’s ground stations at Mauritius, Bengaluru, SDSC-SHAR and Port Blair tracked the satellite during this operation, while a transportable terminal currently stationed in the Fiji islands for Aditya-L1 will support post-burn operations, the Indian space agency added.
ISRO further said that the new orbit attained is 256 km x 121973 km. The next manoeuvre Trans-Lagragean Point 1 Insertion (TL1I), a send-off from the Earth is scheduled for September 19, around 02:00 Hrs. IST, it added.
ISRO’s Aditya-L1 is the first Indian space-based mission, that will study the Sun from a halo orbit around the first Sun-Earth Lagrangian point (L1). This is located approximately 1.5 million km from the planet Earth.
Earlier, all three earth-bound manoeuvres were successfully performed in September month.
During the spacecraft’s 16-day journey around the Earth, the manoeuvres were performed. During this time, the spacecraft will gain the necessary velocity for its further journey to L1.
After completing the fourth earth-bound orbital manoeuvres, the ISRO’s Aditya L1 solar mission will further undergo a Trans-lagrangian1 insertion manoeuvre. This will mark the beginning of its nearly 110-day trajectory to the destination around the L1 Lagrange point.
Another manoeuvre to bind Aditya L1 to an orbit near L1 after arrival at L1 point. This is to be a balanced gravitational location between the Sun and the Earth.
Around L1, the satellite will spend its whole mission life in an irregularly shaped orbit in a plane roughly perpendicular to the line joining the Sun and the Earth.
On September 2, the Aditya L1 spacecraft was successfully launched by ISRO’s Polar Satellite Launch Vehicle (PSLV-C57) from the Second Launch pad of Satish Dhawan Space Centre (SDSC), Sriharikota.
The Aditya L1 was successfully injected into an elliptical orbit of 235×19500 km around the Earth after a flight duration of 1 hour 3 minutes and 20 seconds.
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Aditya L1 successfully undergoes third earth-bound manoeuvre, fourth to take place on September 15: ISRO
India’s first solar mission, the Aditya L1 spacecraft, successfully underwent its third earth-bound orbit raising manoeuvre on Sunday, the Indian Space Research Organisation said.

India’s first solar mission, the Aditya L1 spacecraft, successfully underwent its third earth-bound orbit raising manoeuvre on Sunday, the Indian Space Research Organisation said.
The Telemetry, Tracking, and Command Network (ISTRAC) in Bengaluru oversaw the orbit-raising manoeuvre, with Mauritius, Bengaluru, and Port Blair ground stations tracking the satellite during the critical operation. India’s first solar mission is now one step closer to its ultimate destination after this successful manoeuvre, with the satellite’s new orbit at 296 km x 71767 km.
ISRO shared this picture on its official Instagram page.

The Indian Space Research Organisation (ISRO) has scheduled the next manoeuvre for September 15 at around 2 am. The mission to study the sun, which is part of ISRO’s ambitious plans, was launched successfully on September 2 from the Satish Dhawan Space Centre in Andhra Pradesh’s Sriharikota.
The Aditya-L1 spacecraft has already completed two orbital manoeuvres around the Earth and is set to perform one more before being placed in transfer orbit towards the Lagrange point L1. It is expected to reach its destination after 125 days. Earlier, the Aditya-L1 satellite shared a breathtaking image of the Earth and the Moon.
The spacecraft will observe the Sun from the Lagrange point 1 or L-1 point, which is located 1.5 million km away from the Earth. ISRO states that a spacecraft placed in the halo orbit around the L1 point can continuously view the Sun without any occultation or eclipses. This provides a significant advantage in observing solar activities and their effect on space weather in real time.
The mission aims to study various aspects of the sun, such as the physics of the solar corona and how it is heated, the acceleration of solar wind, the coupling and dynamics of the solar atmosphere, the temperature anisotropy and distribution of solar wind, and the causes of Coronal Mass Ejections (CME) and flares, as well as near-earth space weather.
The successful launch of the Aditya-L1 spacecraft, carried by the PSLV rocket, is a remarkable achievement for ISRO, which is one of the leading space agencies in the world. Prior to the sun mission, ISRO’s Chandrayaan-3 successfully soft-landed near the south pole of the moon, making India the first country to achieve this feat in that region and the fourth on the moon’s surface.