English हिन्दी
Connect with us

Latest world news

China clones 5 gene-edited monkeys to aid disorder research

Published

on

[vc_row][vc_column][vc_column_text]On Thursday, Chinese scientists announced that they had cloned five monkeys from a single animal that was genetically engineered to have a sleep disorder, saying it could aid research into human psychological problems.

The claim, detailed in two reports published in a Chinese science journal, is the latest in a series of biomedical advances in the country, some of which have fuelled medical ethics debates.

Macaques are chiefly Asian monkeys typically having a sturdy build and including some short-tailed or tailless forms. The gene-edited macaque had circadian rhythm disorders associated with depression, diabetic, cancer and Alzheimer’s disease.

It is the first time multiple monkeys have been cloned from a gene-edited monkey for biomedical research, IANS quoted a Xinhua news agency report.

Poo Muming, the director of the neuroscience institute and the study’s co-author, told state media that the research team would seek to clone more monkeys with different brain disorders in hopes that future experiments on them could yield new drugs or treatment.

The cloned monkeys, closer to humans in terms of activity routines, brain structure and metabolic rate, make better models for research on disease pathogenesis and potential therapeutic treatments, according to the team from Institute of Neuroscience of Chinese Academy of Sciences in Shanghai.

To create an ideal donor monkey, the researchers knocked out BMAL1, a core circadian regulatory transcription factor, using gene editing at the embryo stage.

They selected one of the gene-edited monkeys with the most severe disease phenotypes as the donor.

The fibroblasts (the main connective tissue cells present in the body) of the donor were then used to clone five monkeys by somatic cell nuclear transfer, the same method used to generate Zhong Zhong and Hua Hua, the first cloned monkeys born in China at the end of 2017, the report published in the National Science Review journal revealed.

Different from Zhong Zhong and Hua Hua, generated by using fibroblasts from an aborted foetus, the new clones were made using a gene-edited young adult male monkey.

“It shows that besides using foetus, batch cloning of gene-edited male monkeys with diseases is also feasible,” Qiang Sun from the institute, was quoted as saying.

Sun stated the research programme was reviewed and supervised by the institute’s ethic committee in accordance with international ethical standards of animal research, the IANS report said.

In the future, the team plans would focus on cloning monkey models with different brain diseases.

Besides being used to study human brain diseases, the models will be used to test medicine effectiveness, which can help reduce the number of animal models used in experiments and lower the cost of medicine development, the report said.

(Inputs taken from media reports)[/vc_column_text][/vc_column][/vc_row]

Latest world news

China says it will properly handle differences with India ahead of Modi-Xi talks

China has stressed stronger communication and cooperation with India ahead of President Xi Jinping’s bilateral meeting with PM Modi in Delhi.

Published

on

China has said it is ready to strengthen communication and cooperation with India and appropriately manage differences between the two countries ahead of Chinese President Xi Jinping’s meeting with Prime Minister Narendra Modi in New Delhi.

Chinese Ambassador to India Xu Feihong said Beijing and New Delhi were arranging a bilateral meeting between Xi and Modi on the sidelines of the 18th BRICS Summit.

The meeting is scheduled for 5:45 pm on Saturday, according to the report. Xi’s visit marks his return to India after nearly seven years.

China stresses cooperation with India

In a post on X on Friday, Xu said China would work with India in line with the strategic guidance provided by the two leaders.

He said Beijing wanted to approach India-China relations from a strategic and long-term perspective while increasing communication and cooperation.

China said it would properly handle differences and work towards good-neighbourly relations while helping each other succeed. 

Chinese Foreign Ministry spokesperson Mao Ning echoed the position during a media briefing, saying Beijing would work with New Delhi to strengthen communication, expand cooperation and manage differences.

Modi-Xi meeting comes ahead of BRICS Summit

Xi Jinping has travelled to New Delhi to participate in the 18th BRICS Summit, which India is hosting on September 12 and 13.

The Chinese President’s visit comes after a period of strain in India-China relations following the 2020 Galwan Valley clash. Relations have since seen efforts towards stabilisation, including meetings between Modi and Xi in Kazan and Tianjin.

The upcoming meeting in New Delhi will be the third consecutive year in which the two leaders have met, according to the Chinese side.

Xi left Beijing on Saturday for India at the invitation of Prime Minister Modi. His delegation includes senior Chinese officials, including Cai Qi and Wang Yi.

The Modi-Xi bilateral is expected to provide another opportunity for the two sides to maintain high-level engagement while addressing differences in their relationship.

Continue Reading

Latest world news

Iran President Pezeshkian says country will not bow to US, Israel

Iranian President Masoud Pezeshkian, speaking in Delhi, said Iran would not surrender to pressure from the US and Israel and expressed hope for deeper cooperation with India.

Published

on

Iranian President Masoud Pezeshkian on Friday said his country would not surrender to pressure from the United States and Israel, asserting that Iran would continue to push back against what he described as attempts to bully the country.

Pezeshkian made the remarks in New Delhi while addressing Indian religious leaders, intellectuals and business leaders. He had arrived in India earlier in the day to participate in the BRICS Summit.

The Iranian president also expressed hope that his discussions with Prime Minister Narendra Modi would help expand cooperation between India and Iran across several areas.

Pezeshkian says Iran will resist pressure

Speaking about the conflict involving Iran, the US and Israel, Pezeshkian said Iran would not bow to pressure.

He accused the US and Israel of trying to bully Iran and said his country would respond if pushed. Pezeshkian also questioned accusations against Iran and criticised attacks on infrastructure and civilian facilities.

He said the Iranian people would not surrender and emphasised what he described as the importance of equal rights and human values.

Pezeshkian also alleged that 168 schoolchildren were killed in an attack and questioned claims by the US and Israel regarding human rights. These remarks were delivered through a translator, according to the source.

Iran seeks wider cooperation with India

Pezeshkian thanked the Indian government and Prime Minister Modi for the hospitality extended during his visit.

He said his talks with Modi could pave the way for greater cooperation between the two countries in areas including culture, technology, trade, science and the economy.

The Iranian president said India and Iran could work together to revive and strengthen these areas of cooperation.

Modi, Pezeshkian hold bilateral meeting

Modi met Pezeshkian on the sidelines of the BRICS Summit in New Delhi. It was the second meeting between the two leaders in less than two weeks.

They had previously met on the sidelines of the SCO Summit in Bishkek on August 31.

During their latest meeting, the two leaders discussed various aspects of India-Iran relations. Modi thanked Iran for its continued high-level participation in BRICS-related meetings despite the challenging circumstances.

The Prime Minister also thanked Pezeshkian for taking part in the Leaders’ Session of the BRICS Business Forum.

India reiterates call for dialogue

According to the PMO release cited in the report, Modi and Pezeshkian exchanged views on recent developments in West Asia.

Modi reiterated India’s position that issues should be resolved through dialogue and diplomacy. He also stressed the importance of efforts aimed at achieving lasting peace and stability in the region.

The Prime Minister highlighted the need to safeguard freedom of navigation and commerce as well as the safety and well-being of seafarers.

The two sides also discussed continued cooperation on issues of mutual interest in multilateral organisations, including BRICS.

Continue Reading

Latest world news

PM Modi, Iran President Pezeshkian discuss West Asia crisis and trade ties in Delhi

PM Modi met Iranian President Masoud Pezeshkian in Delhi amid West Asia tensions, with talks focusing on regional stability, seafarer safety and India-Iran ties.

Published

on

Prime Minister Narendra Modi met Iranian President Masoud Pezeshkian in New Delhi on Friday for bilateral talks held on the sidelines of the BRICS Summit. The meeting came amid heightened tensions in the Middle East and focused on regional stability, maritime safety and strengthening India-Iran ties.

Pezeshkian arrived in India to attend the BRICS Summit and held discussions with PM Modi for the second time in less than two weeks. Modi had earlier met the Iranian president on August 31 on the sidelines of the Shanghai Cooperation Organisation (SCO) Summit in Bishkek.

During Friday’s meeting, PM Modi highlighted India’s concerns over the continuing crisis in West Asia. He stressed that the safety and security of seafarers remains a top priority for India.

India also reiterated its position that a lasting solution to the regional crisis must come through dialogue and diplomacy. Energy security was another key concern, with India emphasising the need for safe passage for vessels carrying supplies.

The talks took place against the backdrop of the wider Middle East crisis, including the blockade of the Strait of Hormuz, which has raised concerns over energy security and maritime trade. 

Pezeshkian calls for greater BRICS economic resilience

Earlier on Friday, Pezeshkian addressed the BRICS Business Forum and called for greater economic cooperation among member countries.

He said BRICS should focus on strengthening its economic resilience and advocated the use of national currencies for trade among member countries. The Iranian president also argued that the grouping should work toward reducing dependence on the US dollar.

Pezeshkian criticised US sanctions and military actions, saying BRICS should create conditions where legitimate trade cannot be disrupted by the monopolisation of financial instruments.

Modi and Pezeshkian had met in Bishkek

PM Modi and Pezeshkian had last met on August 31 in Bishkek. During that meeting, Modi said India wanted to strengthen its longstanding friendship with Iran and expand and diversify bilateral trade.

The two leaders also discussed developments in the West Asia conflict. Modi reiterated India’s position that disputes should be addressed through dialogue and diplomacy and stressed the importance of protecting civilians, commercial shipping and seafarers.

During the earlier meeting, Pezeshkian had sought India’s diplomatic support in encouraging the conflicting sides to move away from violence and return to negotiations.

The latest Modi-Pezeshkian talks come as India hosts the BRICS Summit in New Delhi, with the regional crisis and its impact on the global economy forming an important backdrop to the high-level discussions.

Continue Reading

Trending

© Copyright 2022 APNLIVE.com