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China clones 5 gene-edited monkeys to aid disorder research

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[vc_row][vc_column][vc_column_text]On Thursday, Chinese scientists announced that they had cloned five monkeys from a single animal that was genetically engineered to have a sleep disorder, saying it could aid research into human psychological problems.

The claim, detailed in two reports published in a Chinese science journal, is the latest in a series of biomedical advances in the country, some of which have fuelled medical ethics debates.

Macaques are chiefly Asian monkeys typically having a sturdy build and including some short-tailed or tailless forms. The gene-edited macaque had circadian rhythm disorders associated with depression, diabetic, cancer and Alzheimer’s disease.

It is the first time multiple monkeys have been cloned from a gene-edited monkey for biomedical research, IANS quoted a Xinhua news agency report.

Poo Muming, the director of the neuroscience institute and the study’s co-author, told state media that the research team would seek to clone more monkeys with different brain disorders in hopes that future experiments on them could yield new drugs or treatment.

The cloned monkeys, closer to humans in terms of activity routines, brain structure and metabolic rate, make better models for research on disease pathogenesis and potential therapeutic treatments, according to the team from Institute of Neuroscience of Chinese Academy of Sciences in Shanghai.

To create an ideal donor monkey, the researchers knocked out BMAL1, a core circadian regulatory transcription factor, using gene editing at the embryo stage.

They selected one of the gene-edited monkeys with the most severe disease phenotypes as the donor.

The fibroblasts (the main connective tissue cells present in the body) of the donor were then used to clone five monkeys by somatic cell nuclear transfer, the same method used to generate Zhong Zhong and Hua Hua, the first cloned monkeys born in China at the end of 2017, the report published in the National Science Review journal revealed.

Different from Zhong Zhong and Hua Hua, generated by using fibroblasts from an aborted foetus, the new clones were made using a gene-edited young adult male monkey.

“It shows that besides using foetus, batch cloning of gene-edited male monkeys with diseases is also feasible,” Qiang Sun from the institute, was quoted as saying.

Sun stated the research programme was reviewed and supervised by the institute’s ethic committee in accordance with international ethical standards of animal research, the IANS report said.

In the future, the team plans would focus on cloning monkey models with different brain diseases.

Besides being used to study human brain diseases, the models will be used to test medicine effectiveness, which can help reduce the number of animal models used in experiments and lower the cost of medicine development, the report said.

(Inputs taken from media reports)[/vc_column_text][/vc_column][/vc_row]

Latest world news

Israel-Lebanon ceasefire to begin within hours as Trump announces 10-day truce

Israel and Lebanon may begin a 10-day ceasefire within hours after a proposal announced by Donald Trump amid ongoing tensions.

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Donald Trump

A temporary halt in hostilities between Israel and Lebanon is expected to begin within hours after US President Donald Trump announced a proposed 10-day ceasefire between the two sides, amid ongoing tensions in the region.

According to his statement, the ceasefire is likely to take effect around 5 p.m. Eastern Time, although independent confirmation from both sides is still awaited.

The development follows discussions involving Israeli Prime Minister Benjamin Netanyahu and Lebanese President Joseph Aoun, with mediation efforts led by the United States.

Officials indicated that the proposed truce is aimed at creating a limited window to reduce violence and potentially pave the way for broader diplomatic engagement. The situation along the Israel-Lebanon border has remained tense in recent weeks, with escalation linked to the activities of Hezbollah.

Diplomatic efforts have intensified in recent days, with discussions facilitated by the United States, including the involvement of US Secretary of State Marco Rubio. However, details of the agreement and the extent of coordination between the parties remain unclear.

The situation remains fluid, and the success of the ceasefire will depend on adherence by all sides involved. The conflict has already led to significant humanitarian and geopolitical consequences, including displacement and disruption in affected areas.

While the proposed ceasefire is being seen as an important step toward de-escalation, broader negotiations involving regional stakeholders are expected to be necessary for any lasting resolution.

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US ends oil sanctions waiver for Iran and Russia, impact likely on India’s energy imports

The US decision to end the Iran and Russia oil waiver may impact India’s oil imports, fuel prices and global energy markets.

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US oil tanker

The United States has decided not to extend a temporary sanctions waiver that allowed limited trade in Iranian and Russian oil, marking a shift towards stricter enforcement of economic restrictions.

The waiver, introduced in March 2026, had permitted the sale of oil already loaded on ships to stabilise global supply during heightened geopolitical tensions. However, it is now set to expire around mid-April without renewal.

US officials have indicated that the move is part of a broader strategy to increase pressure on both Iran and Russia amid ongoing conflicts and geopolitical tensions.

What the waiver did and why it mattered

The short-term waiver allowed millions of barrels of oil—estimated at around 140 million barrels—to enter global markets, helping ease supply shortages and prevent sharp price spikes.

It also enabled countries like India to purchase discounted crude oil from Russia and resume limited imports from Iran after years of restrictions.

Impact on India

India, one of the world’s largest oil importers, is expected to feel the impact of the decision in several ways:

  • Reduced access to discounted oil
    India had been buying cheaper Russian crude and recently resumed Iranian imports under the waiver. Its end may limit these options.
  • Potential rise in fuel costs
    With fewer discounted supplies available, India may need to rely more on costlier sources, which could increase domestic fuel prices.
  • Supply diversification pressure
    India may need to explore alternative suppliers in the Middle East, Africa, or the US to maintain energy security.
  • Geopolitical balancing challenge
    The move adds pressure on India to align with US sanctions while managing its own economic interests.

Global energy market concerns

The end of the waiver comes at a time when global oil markets are already under stress due to conflict in West Asia and disruptions in key routes like the Strait of Hormuz.

Analysts warn that tightening sanctions could:

  • Reduce global oil supply
  • Increase price volatility
  • Intensify competition among major buyers like India and China

Bigger picture

The US decision reflects a broader shift from temporary relief measures to stricter enforcement of sanctions, even if it risks tightening global energy markets.

For India, the development highlights a recurring challenge—balancing affordable energy access with geopolitical realities.

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Sanctioned tanker fails to breach US blockade, turns back near Strait of Hormuz

A US-sanctioned tanker failed to cross the Hormuz blockade and turned back, underscoring rising tensions and disruption in global shipping routes.

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A US-sanctioned oil tanker failed to break through a newly imposed American naval blockade and was forced to turn back near the Strait of Hormuz, highlighting growing tensions in the region.

The vessel, identified as the Rich Starry, reversed its course after attempting to exit the Gulf, according to shipping data. The development comes just days after the United States enforced restrictions on ships linked to Iranian ports.

The blockade was announced by Donald Trump following the collapse of recent diplomatic talks with Iran. The move aims to restrict maritime traffic associated with Iranian trade.

Officials said that during the first 24 hours of enforcement, no vessel successfully crossed the blockade. Several ships, including the sanctioned tanker, complied with instructions from US forces and turned back toward regional waters.

The tanker is reported to be linked to a Chinese company previously sanctioned for dealing with Iran. It was carrying a cargo of methanol loaded from the United Arab Emirates at the time of the incident.

The situation underscores the rising risks in one of the world’s most critical oil transit routes. The Strait of Hormuz typically handles a significant share of global energy shipments, but traffic has sharply declined due to ongoing geopolitical tensions.

The blockade, which applies specifically to vessels travelling to or from Iranian ports, has added further uncertainty for shipping companies, insurers and global energy markets.

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