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China clones 5 gene-edited monkeys to aid disorder research

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[vc_row][vc_column][vc_column_text]On Thursday, Chinese scientists announced that they had cloned five monkeys from a single animal that was genetically engineered to have a sleep disorder, saying it could aid research into human psychological problems.

The claim, detailed in two reports published in a Chinese science journal, is the latest in a series of biomedical advances in the country, some of which have fuelled medical ethics debates.

Macaques are chiefly Asian monkeys typically having a sturdy build and including some short-tailed or tailless forms. The gene-edited macaque had circadian rhythm disorders associated with depression, diabetic, cancer and Alzheimer’s disease.

It is the first time multiple monkeys have been cloned from a gene-edited monkey for biomedical research, IANS quoted a Xinhua news agency report.

Poo Muming, the director of the neuroscience institute and the study’s co-author, told state media that the research team would seek to clone more monkeys with different brain disorders in hopes that future experiments on them could yield new drugs or treatment.

The cloned monkeys, closer to humans in terms of activity routines, brain structure and metabolic rate, make better models for research on disease pathogenesis and potential therapeutic treatments, according to the team from Institute of Neuroscience of Chinese Academy of Sciences in Shanghai.

To create an ideal donor monkey, the researchers knocked out BMAL1, a core circadian regulatory transcription factor, using gene editing at the embryo stage.

They selected one of the gene-edited monkeys with the most severe disease phenotypes as the donor.

The fibroblasts (the main connective tissue cells present in the body) of the donor were then used to clone five monkeys by somatic cell nuclear transfer, the same method used to generate Zhong Zhong and Hua Hua, the first cloned monkeys born in China at the end of 2017, the report published in the National Science Review journal revealed.

Different from Zhong Zhong and Hua Hua, generated by using fibroblasts from an aborted foetus, the new clones were made using a gene-edited young adult male monkey.

“It shows that besides using foetus, batch cloning of gene-edited male monkeys with diseases is also feasible,” Qiang Sun from the institute, was quoted as saying.

Sun stated the research programme was reviewed and supervised by the institute’s ethic committee in accordance with international ethical standards of animal research, the IANS report said.

In the future, the team plans would focus on cloning monkey models with different brain diseases.

Besides being used to study human brain diseases, the models will be used to test medicine effectiveness, which can help reduce the number of animal models used in experiments and lower the cost of medicine development, the report said.

(Inputs taken from media reports)[/vc_column_text][/vc_column][/vc_row]

Latest world news

Trump approves nearly $9 billion weapons sales to Israel, UAE and other allies amid Iran tensions

The US has fast-tracked nearly $9 billion in weapons sales to Israel, UAE and other allies as tensions linked to the Iran conflict continue despite a fragile ceasefire.

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Donald Trump statement

The United States has approved nearly $9 billion worth of weapons sales to key Middle Eastern allies, including Israel and the United Arab Emirates, amid ongoing tensions linked to the Iran conflict.

The decision, cleared by the administration of Donald Trump, includes expedited military transfers to Israel, the UAE, Qatar, and Kuwait. The approvals were granted under an emergency provision, allowing authorities to bypass the usual congressional review process.

Emergency clearance amid ongoing conflict

Officials said the move was necessary due to the evolving security situation in the region, particularly as the conflict involving Iran continues despite a fragile ceasefire. The war, which began earlier in 2026, has heightened instability across West Asia.

US Secretary of State Marco Rubio invoked emergency powers to fast-track the deals, citing urgent defence requirements for allied nations.

What the arms package includes

The approved package includes a mix of advanced defence systems and precision weapons:

  • Patriot missile defence replenishments worth over $4 billion for Qatar
  • Precision-guided weapon systems for multiple countries
  • Integrated battle command systems for Kuwait
  • Additional advanced weapons support for Israel and the UAE

The total value of these deals is estimated at over $8.6 billion, often rounded to nearly $9 billion.

Timing linked to iran war

The approval comes nearly nine weeks into the conflict involving the US, Israel, and Iran, with tensions still high despite a ceasefire that has been in place for several weeks.

Analysts note that the move signals continued US military backing for its regional allies, particularly in strengthening air defence and precision strike capabilities during uncertain conditions.

Criticism and concerns

The decision to bypass congressional oversight has drawn criticism from some quarters, particularly over transparency and the broader implications of increasing arms supplies in a conflict-prone region.

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Trump and Putin hold over 90-minute call, discuss Iran war and Ukraine conflict

Trump and Putin held a 90-minute call focusing on Iran tensions and the Ukraine conflict, with warnings over escalation and talks of ceasefire.

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Vladimir Putin and Donald Trump

US President Donald Trump and Russian President Vladimir Putin held a phone conversation lasting more than 90 minutes, focusing on escalating tensions in the Middle East and the ongoing war in Ukraine.

According to official statements, the discussion was described as “frank and businesslike,” with both leaders addressing key global security concerns. A major part of the conversation centred on the situation involving Iran and developments in the Persian Gulf.

Putin supported Trump’s decision to extend the ceasefire related to Iran, suggesting that continued restraint could create space for negotiations and help stabilise the region. However, he also issued a strong warning, stating that renewed military action by the United States or Israel could lead to “extremely damaging consequences” not only for Iran but for the wider international community.

Ukraine conflict also discussed

The leaders also discussed the ongoing war in Ukraine, which has continued for several years since Russia’s invasion in 2022. During the call, there were indications of potential efforts toward a temporary ceasefire, although no final agreement has been confirmed.

Reports suggest that the idea of a short-term pause in hostilities was explored, possibly linked to upcoming symbolic dates, but significant differences between the parties remain unresolved.

Focus on diplomacy amid global tensions

The call highlights ongoing diplomatic engagement between Washington and Moscow at a time of heightened geopolitical tensions involving both the Middle East and Eastern Europe.

While both sides acknowledged the importance of dialogue, the situation on the ground in both conflict zones remains complex, with no immediate resolution in sight.

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Trump rejects Iran peace plan as tensions rise, Tehran signals military readiness

Trump rejects Iran’s peace plan, keeping focus on nuclear concerns as Tehran signals readiness and tensions continue to rise.

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Donald Trump statement

U.S. President Donald Trump has rejected a proposal from Iran aimed at easing ongoing tensions, signaling a continued deadlock between the two countries.

The proposal reportedly included steps linked to easing restrictions around the Strait of Hormuz, a key global oil route. However, the United States declined the offer, maintaining that any agreement must address concerns related to Iran’s nuclear programme.

Washington has made it clear that resolving nuclear issues remains a priority and that partial measures without broader commitments will not be accepted.

Nuclear issue remains central

The U.S. position continues to focus on preventing Iran from advancing its nuclear capabilities. Officials believe that without a comprehensive agreement, temporary arrangements could delay a long-term resolution.

The rejection of the proposal indicates that negotiations remain stalled, with both sides holding firm on key demands.

Iran issues warning

Following the rejection, Iranian officials have issued strong statements, indicating readiness to respond if pressure from the U.S. continues.

Reports suggest that Iran has asserted its military preparedness, warning that any escalation could lead to serious consequences. The remarks reflect growing tensions as diplomatic efforts struggle to produce results.

Rising geopolitical tension

The situation remains volatile, with both countries engaged in a prolonged standoff. Measures such as restrictions on trade routes and strategic pressure points continue to impact the broader region.

The Strait of Hormuz remains a critical factor in the conflict, given its importance for global energy supplies.

Outlook uncertain

With no immediate breakthrough in sight, tensions between the United States and Iran are expected to persist. The lack of agreement on key issues, particularly the nuclear programme, continues to hinder progress toward de-escalation.

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